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Strength and Endurance Training in the Treatment of Advanced Lung Cancer Patients

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Strength and Endurance Training in the Treatment of Advanced Lung Cancer Patients

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Palliative chemotherapy offers an improvement in survival in NSCLC patients. In patients with a good performance status, first-line platinum-based chemotherapy regimes are recommended. Although side effects are reduced compared to former therapies, patients still experience severe side effects and unpleasant symptoms. Since all symptoms have not only an effect on the physical activity level, but also have a psychological impact and influence the patient’s social status, quality of life (QOL) is often tremendously reduced. In performing activities of daily living patients often depend on other people and therefore are not able to keep their activity level up. It is a considerable challenge in the field of physiotherapy to maintain the patient’s strength and mobility. Maintenance of the patient’s physical fitness might also improve the patient’s tolerance level concerning chemotherapy, since symptoms and side effects might be reduced. As a result physiotherapy might not only have a positive impact on the patient’s activity level and independence, but also affect the patient’s psychosocial status, which again influences the patient’s quality of life. Therefore we set up a research study in order to detect the effects of physiotherapy on the quality of life in advanced lung cancer patients. For the conduction of this randomized controlled trial, which will start in July 2009, we include patients with stage IIIB/IV NSCLC and a good performance status (WHO 0, 1, 2, 3 or a Karnofsky score of 40-100). Every participant should be at least 18 years old and receive an in-patient chemotherapy treatment at the oncological department of the Vivantes Krankenhaus in Neukoelln/Berlin. All participants will be randomly divided into two groups. The intervention group will receive a specially designed combination of strength and endurance training, whereas the control group will not receive this additional training. The patient will receive this additional physiotherapeutical training while receiving three cycles of chemotherapy. Blood pressure, heart rate, temperature and haemoglobin will be regularly checked and documented to test the patient’s condition. In both groups participants will fill out the Barthel index and the EORTC QLQ C-30 questionnaire prior to and after the intervention in order to report the patient’s activity level and quality of life. The obtained data will be statistically analyzed and interpreted in the end of the designed intervention. Additionally the Six Minute Walk Test will be used to test the patient’s endurance capacity and level of dyspnoea while making also use of the Modified Borg Scale. Any effects in the patient’s strength will be reported and analysed by the amount of repetitions a patient can perform in one specific exercise. The aim of our study is to test the impact of physiotherapy with a combination of strength and endurance training on quality of life in NSCLC patients stage IIIB/IV, receiving chemotherapy as palliative treatment.

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OrganisatieHogeschool van Amsterdam
InstituutGezondheid
Gepubliceerd in
Jaar2009
TypeBachelorscriptie
TaalEngels

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