What is the best evidence based protocol, for the treatment of stroke in the acute phase, as compared to the existing protocol for the patients at Universitair Ziekenhuis Antwerpen, (UZA) Belgium? We made our protocol according to his demand. In our research of medical literature we found recent articles explaining the physiotherapeutic interventions in acute phase. In these articles we also found topics that were not discussed in the KNGF guidelines. Conclusion(s): According to our research Mirror therapy and Ankle foot orthosis (AFO) should be the part of physiotherapy of stroke patients in acute phase. Recommendations/suggestion for further research/projects: KNGF guidelines are still applicable – but, in our opinion, need to be updated.