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How valid are predictive equations to estimate resting energy expenditure in obese elderly

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How valid are predictive equations to estimate resting energy expenditure in obese elderly

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Samenvatting

Introduction: Equations are often used to predict resting energy expenditure (REE), because measuring REE using indirect calorimetry (IC) is hardly feasible in practice. It is unknown whether predictive equations are valid to estimate REE in obese elderly. Therefore the aim of this thesis is to investigate the validity of predictive equations to estimate REE in obese elderly compared to IC. Methods: Thirty predictive equations for estimating REE were tested and included, of which twenty equations based on weight and ten equations based on fat free mass (FFM). REE was measured in 44 Dutch obese elderly (age ≥ 55 y) using IC. The validity of the predictive equations was determined by comparing predicted REE to measured REE by using the following statistical tests: the percentage of accurate predictions (within 10% of REE measured), root mean squared error (RMSE), concordance correlation coefficient (CCC) and the mean bias. Results: The three equations giving best results for predicting REE in obese elderly when comparing accurate predictions, RMSE, CCC and bias are the equations of Harris & Benedict 1984 (68% accurate predictions; RMSE 189 kcal/d; CCC 0.731; bias -72 kcal/d), Huang et al. (68% accurate predictions; RMSE 189 kcal/d; CCC 0.754; bias -50 kcal/d) and Korth et al. (66% accurate predictions; RMSE 188 kcal/d; CCC 0.769; bias 7 kcal/d). Of all equations in this study most formulas underestimate REE more often than they overestimate REE. Equations using FFM provided no advantage for accurately estimating REE compared to equations using weight only. Conclusion: The equations of Harris & Benedict 1984, Huang et al. and Korth et al. are accurate for predicting REE in obese elderly. The equations of Huang et al. and Korth et al. are probably not very well known in dietary practice. The Harris & Benedict 1984 equation however is one of the most commonly used formulas in dietary practice. It is therefore advisable to use the Harris & Benedict 1984 equation for predicting REE in obese elderly.

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OrganisatieHogeschool van Amsterdam
InstituutBewegen, Sport en Voeding
Gepubliceerd in
Jaar2012
TypeBachelorscriptie
TaalEngels

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