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Welprex study : The relation between dietary protein intake and change in blood pressure in overweight adults during a 10 week weight loss program

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Welprex study : The relation between dietary protein intake and change in blood pressure in overweight adults during a 10 week weight loss program

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Backgrounds Obesity increases the risk of various conditions such as hypertension. Previous studies show that protein intake may have beneficial effects on blood pressure. Aim This study aims to examine the relation between dietary protein intake and changes in blood pressure in overweight adults during a 10 week weight loss program. We expect that a hypocaloric diet high in protein leads to a greater drop in blood pressure levels compared to a hypocaloric diet with normal protein intake. Furthermore, we anticipate that vegetable protein has a stronger significant lowering effect compared to animal protein. We compared the effect of a hypocaloric diet with normal protein intake (C) and a high protein diet (HP) on blood pressure levels. Methods Overweight adults were recruited in Amsterdam-West. Subjects from whom the blood pressure measurements were performed at baseline and at the end measurement and who handed in the three-day dietary record were included for analysis. Subjects were randomised in one of the two interventions: control (hypocaloric with normal protein intake 0.8 g protein /kg bodyweight) or high protein (hypocaloric with high protein intake, 1.3g protein /kg bodyweight). Blood pressure measurements from the baseline and end measurement were used for analysis. Dietary energy and total, plant and animal protein intake were measured through a three-day dietary food record handed in, at baseline, after 5 weeks and after 10 weeks. Results After meeting the eligibility criteria, 33 participants were included in the study. The systolic blood pressure decreased with -12.4 12 mmHg in the control group and with -13.7 15.1 mmHg in the HP group. No significant differences were found in systolic (P=0.786) and diastolic blood pressure (P=0.371) between the groups. The diastolic blood pressure decreased with -8.5 7.3 mmHg in the control group and -5.89.2 mmHg in the HP group. Weight loss confounded the relation between total dietary protein and blood pressure. Therefore, the data was corrected for weight loss.For each gram of total protein intake extra, the systolic blood pressure dropped non-significantly with -0.012 (P=0.919) and the diastolic decreased non-significantly with -0.009 (P=0.908). Conclusion Results showed that total protein intake did not have a significant effect on blood pressure drop in both groups. Therefore, changes in blood pressure probably occurred due to weight loss during the program which is simultaneously found to be a confounder.

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OrganisatieHogeschool van Amsterdam
InstituutBewegen, Sport en Voeding
Gepubliceerd in
Jaar2013
TypeBachelorscriptie
TaalEngels

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