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Epidemiology of cerebral palsy in adulthood: a systematic review and meta-analysis of the most frequently studied outcomes

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Epidemiology of cerebral palsy in adulthood: a systematic review and meta-analysis of the most frequently studied outcomes

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Samenvatting

Objective
To describe the epidemiology of health status, impairments, activities and participation in adults with cerebral palsy (CP).

Data Sources
Embase, MEDLINE, Web of Science, PsycINFO, Cumulative Index to Nursing and Allied Health, Cochrane, and Google Scholar were searched for 3 themes (“cerebral palsy,” “adult,” and “outcome assessment”) in literature published between January 2000 and December 2018.

Study Selection
Full-article peer-reviewed English journal articles on descriptive, observational, or experimental studies describing the most studied outcomes in adults with CP (n≥25, age≥18y) were included. Studies were included in the analyses if frequently studied outcomes were described in at least 3 studies using similar methods of assessment.

Data Extraction
Data were extracted independently by 2 authors from 65 articles (total N=28,429) using a standardized score sheet.

Data Synthesis
Meta-analyses revealed that overall, on average 65.1% (95% confidence interval [CI], 55.1-74.5) of adults with CP experienced pain, 57.9% (95% CI, 51.1-64.6) were ambulant, 65.5% (95% CI, 61.2-69.7) had little or no limitation in manual ability, 18.2% (95% CI, 10.6-27.2) had tertiary education, 39.2% (95% CI, 31.5;47.1) were employed, and 29.3% (95% CI, 9.0-55.3) lived independently. In adults without intellectual disability, proportions of individuals who were ambulant (72.6% [95% CI, 58.8-84.5]) and lived independently (90.0% [95% CI, 83.8-94.9]) were higher (P=.014 and P

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OrganisatieHogeschool Rotterdam
LectoraatKenniscentrum Zorginnovatie
Gepubliceerd inArchives of Physical Medicine and Rehabilitation Vol. 101 (2020), Uitgave: 6 (June 2020), Pagina's: 1041-1052
Datum2020-02-12
TypeArtikel
ISSN0003-9993
DOI10.1016/j.apmr.2020.01.009
TaalEngels

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