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Computed ultra high b value diffusion-weighted MR imaging of the prostate

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Computed ultra high b value diffusion-weighted MR imaging of the prostate

Rechten: Alle rechten voorbehouden

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abstract voor het European Congress of Radiology (ECR):

Purpose: To investigate if calculated ultra high b value (b3000) diffusion weighted imaging provides higher positive predictive value for prostate cancer, compared to high b value images (b1400).
Methods and Materials: 21 patients, suspected of prostate cancer, underwent multiparametric MRI. The MR exam consisted of both calculated b1400 and calculated b3000 sequences. In two cases also an acquired b3000 DWI series was made. Patient studies were independently reviewed by two readers. Different forms were scored: first, if abnormalities suspected of cancer, were seen on calculated b1400 and on b3000 images. Second, image quality and diagnostic value were assessed for calculated b1400, calculated b3000 and acquired b3000 images. Third, if abnormalities suspected of cancer, were seen on calculated b3000 and on acquired b3000 images. Pathological findings from either biopsy or prostatectomy served as reference standard.
Results: For reader 1 there was no difference in PPV for calculated b1400 and b3000 (89.5% both series). Reader 2 achieved better result on the b3000 series (87.5%) compared to b1400 (84.6%). (McNemar for number of scored lesions not significant: p 1,000 and 0.500). Regarding image quality: calculated b3000 series had highest tumour-Periferal Zone contrast and highest suppression of normal tissue (Friedman rank: statistically significant: p 0.000 and 0.002). Due to very small number of patients for acquired b3000 series, PPV could not be assessed for acquired b3000 images.
Conclusion: An individual reader can benefit from calculated b3000 images and achieve higher PPV.

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OrganisatieHogeschool Inholland
InstituutDomein Gezondheid, Sport en Welzijn
LectoraatMedische Technologie
Gepubliceerd in
Datum2016-04-01
TypeAndersoortig materiaal
TaalOnbekend

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