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Treatment planning of stereotactic radiosurgery for single brain metastases: impact of leaf width

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Rechten:Alle rechten voorbehouden

Treatment planning of stereotactic radiosurgery for single brain metastases: impact of leaf width

Open access

Rechten:Alle rechten voorbehouden

Samenvatting

Purpose/objective: Stereotactic radiosurgery of brain metastases requires highly conformal dose distributions. Besides beams setup, characteristics of the linear accelerator collimator may also play a role. In this study we compared the impact of leaf width on the dose outside the target for stereotactic radiosurgery of single brain metastases.

Results: The mean dose was evaluated in the first 2 rings of 5 mm around the PTV(table 1). The difference in mean dose for the small lesions(Dpres=24 Gy) of the first ring of 5 mm is 1.8 Gy in favor of the Agility and 0.9 Gy for the larger lesions(Dpres=18 Gy)also in favor of the Agility. The difference is smaller for the larger lesions (figure1). Also for the second ring of 5 mm, adjacent to the first ring, the difference is is 1.1 Gy vs 0.8 Gy also in favor of the Agility.

Conclusion: For the small lesions with a volume smaller than 4 cm³ the Agility shows a steeper gradient in the two surrounding rings than the MLCi1. Therefore we recommend the use of the Agility for treating the smaller lesions.

Toon meer
OrganisatieHogeschool Inholland
AfdelingDomein Gezondheid, Sport en Welzijn
LectoraatMedische Technologie
Datum2015-12-01
TypeArtikel
TaalEngels

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