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Long-term swallowing, trismus, and speech outcomes after combined chemoradiotherapy and preventive rehabilitation for head and neck cancer; 10-year plus update

Karsten, Rebecca T.; van der Molen, Lisette; Hamming-Vrieze, Olga; van Son, RobJ. J. J. H.; Hilgers, Frans J. M.; van den Brekel, Michiel W. M.; Stuiver, Martijn M (Urban Vitality); Smeele, Ludi E.

BACKGROUND: The objective of this study was to explore the 10-year plus outcomes of Intensity Modulated Radiotherapy with concomitant chemotherapy (CRT) combined with preventive swallowing rehabilitation (CRT+) for head and neck cancer (HNC). METHODS: Subjective and objective swallowing, trismus, and …

2020AlgemeenArtikel

Improving Decision Making in Larynx Cancer by Developing a Decision Aid: A Mixed Methods Approach

Petersen, Japke F.; Berlanga, Adriana; Stuiver, Martijn M. (Faculteit Gezondheid); Hamming-Vrieze, Olga; Hoebers, Frank; Lambin, Philippe; van den Brekel, Michiel W.M.

OBJECTIVE: Patients diagnosed with advanced larynx cancer face a decisional process in which they can choose between radiotherapy, chemoradiotherapy, or a total laryngectomy with adjuvant radiotherapy. Clinicians do not always agree on the best clinical treatment, making the decisional process for patients …

2019-12AlgemeenArtikel

Study protocol of a prospective multicenter study comparing (cost-)effectiveness of a tailored interdisciplinary head and neck rehabilitation program to usual supportive care for patients treated with concomitant chemo- or bioradiotherapy

Beck, Ann-Jean C C; Passchier, Ellen; Retèl, Valesca P; Stuiver, Martijn M (Urban Vitality); van der Molen, Lisette; Klop, Willem M C; Navran, Arash; van Harten, Wim H; van den Brekel, Michiel W M

BACKGROUND: Since 2011, a tailored, interdisciplinary head and neck rehabilitation (IHNR) program, covered by the basic healthcare insurance, is offered to advanced head and neck cancer (HNC) patients in the Netherlands Cancer Institute (NKI). This program is developed to preserve or restore patients' …

2019-07-03AlgemeenArtikel

Mapping the EORTC QLQ-C30 and QLQ-H&N35 to the EQ-5D for head and neck cancer

Beck, Ann-Jean C C; Kieffer, Jacobien M; Retèl, Valesca P; van Overveld, Lydia F J; Takes, Robert P; van den Brekel, Michiel W M; van Harten, Wim H; Stuiver, Martijn M (Lectoraat Functioneel Herstel Bij Kanker)

INTRODUCTION: Innovations in head and neck cancer (HNC) treatment are often subject to economic evaluation prior to their reimbursement and subsequent access for patients. Mapping functions facilitate economic evaluation of new treatments when the required utility data is absent, but quality of life …

2019AlgemeenArtikel

Sarcopenia, a strong determinant for prolonged feeding tube dependency after chemoradiotherapy for head and neck cancer

Karsten, Rebecca T.; Al-Mamgani, Abrahim; Bril, Sandra I.; Tjon-A-Joe, Sheena; van der Molen, Lisette; de Boer, Jan P.; Hilgers, Frans J. M.; Smeele, Ludi E.; van den Brekel, Michiel W. M.; Stuiver, Martijn M.

BACKGROUND: Sarcopenia might be a relevant lead for optimization of the condition of patients with head and neck cancer (HNC) before chemoradiotherapy (CRT) to prevent long-term functional swallowing impairment, such as feeding tube dependency. METHODS: Regression analyses were performed to assess the …