Owing to the non-toxic, nonimmunogenic effects and high affinity to specific molecules, some single-stranded oligonucleotides, namely aptamers, can be exploited in biochemical applications to deliver bioactive elements and interact with the desired targets. Among many identified aptamers, D#7 was utilized …

In the present study, effects of Genre Writing instruction added with planning and revising activities (GWPR) are investigated in teacher education. This type of instruction was considered promising because it appeared to lead to positive effects on topic knowledge and insight in previous studies conducted …

Forecasting long-term consequences of global warming requires knowledge on thermal mortality and how heat stress interacts with other environmental stressors on different timescales. Here, we describe a flexible analytical framework to forecast mortality risks by combining laboratory measurements on …

Tumor necrosis factor alpha (TNF-α) and its key role in modulating immune responses has been widely recognized as a therapeutic target for inflammatory and neurodegenerative diseases. Even though inhibition of TNF-α is beneficial for the treatment of certain inflammatory diseases, total neutralization …

The use of Augmented Reality (AR) in industry is growing rapidly, driven by benefits such as efficiency gains and ability to overcome physical boundaries. Existing studies stress the need to take stakeholder values into account in the design process. In this study the impact of AR on stakeholders' values …

Purpose : Adolescents are insufficiently physically active and spent too much time sitting, which provides a health risk. In the current study the municipality of Amsterdam, secondary schools, experts in urban sports and researchers work together to stimulate healthy exercise behavior of adolescents. …

Electrification of residential areas is increasingly common. Major areas of development include promoting rooftop solar panels, electric vehicles and heat pumps. However, existing grid components may have insufficient capacity to support the resulting electricity flows. Battery energy storage (BES) can …

Clonal haematopoiesis of intermediate potential (CHIP) driven by somatic mutations in DNMT3A and TET2 has been recently recognized as a new risk factor for cardiovascular diseases (CVD). The haematopoietic clones with mutations in these genes are frequently found in myeloid malignancies and according …

This paper presents a report of some of the activities of the International Energy Agency's (IEA) Wind TCP Task 39. By identifying best practices in an international collaboration, Task 39 hopes to provide the scientific evidence to inform improved regulations and standards, increasing the effectiveness …

Background: Ventilation with lower positive end–expiratory pressure (PEEP) may cause loss of lung aeration in critically ill invasively ventilated patients. This study investigated whether a systematic lung ultrasound (LUS) scoring system can detect such changes in lung aeration in a study comparing …