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Dead space estimates may not be independently associated with 28-day mortality in COVID-19 ARDS

Morales-Quinteros, Luis; Neto, Ary Serpa; Artigas, Antonio; Blanch, Lluis; Botta, Michela; Kaufman, David A.; Schultz, Marcus J.; Tsonas, Anissa M.; Paulus, Frederique; Bos, Lieuwe D.

BACKGROUND: Estimates for dead space ventilation have been shown to be independently associated with an increased risk of mortality in the acute respiratory distress syndrome and small case series of COVID-19-related ARDS. METHODS: Secondary analysis from the PRoVENT-COVID study. The PRoVENT-COVID is …

2021AlgemeenArtikel

The (cost-)effectiveness of an implemented fall prevention intervention on falls and fall-related injuries among community-dwelling older adults with an increased risk of falls: protocol for the in balance randomized controlled trial

van Gameren, Maaike; Bossen, Daniël (Lectoraat Oefentherapie); Bosmans, Judith E.; Visser, Bart (Centre Of Expertise Urban Vitality); Frazer, Sanne W. T.; Pijnappels, Mirjam

BACKGROUND: Falls and fall-related injuries among older adults are a serious threat to the quality of life and result in high healthcare and societal costs. Despite evidence that falls can be prevented by fall prevention programmes, practical barriers may challenge the implementation of these programmes. …

2021AlgemeenArtikel

The longitudinal association between depressive symptoms and functional abilities in older patients

OBJECTIVES: To investigate the course of depressive symptoms, and basic and instrumental activities of daily living (collectively described as, (I)ADL functioning) from acute admission until one year post-discharge, the longitudinal association between depressive symptoms and (I)ADL functioning, and …

2020-10AlgemeenArtikel

PRactice of VENTilation in Patients with Novel Coronavirus Disease (PRoVENT-COVID)

Boers, Noor S.; Botta, Michela; Tsonas, Annisa M.; Algera, Anna Geke; Pillay, Janesh; Dongelmans, Dave A.; Horn, Janneke; Vlaar, Alexander P. J.; Hollmann, Markus W.; Bos, Lieuwe D. J.; Paulus, Frederique (Lectoraat Critical Care); Neto, Ary Serpa; Schultz, Marcus J.

Background: The coronavirus disease 2019 (COVID-19) pandemic is rapidly expanding across the world, with more than 100,000 new cases each day as of end-June 2020. Healthcare workers are struggling to provide the best care for COVID-19 patients. Approaches for invasive ventilation vary widely between …

2020-10AlgemeenArtikel

Study protocol of a randomized, doubleblind, placebo-controlled, multi-center trial to treat antipsychotic-induced weight gain

Nini de Boer; Sinan Guloksuz; Caroline van Baal; Leonie Willebrands; Jeroen Deenik; Wilma Swildens (Lector)

Abstract Background: Antipsychotic-induced Weight Gain (AiWG) is a debilitating and common adverse effect of antipsychotics. AiWG negatively impacts life expectancy, quality of life, treatment adherence, likelihood of developing type-2 diabetes and readmission. Treatment of AiWG is currently challenging, …

2020-03-08GezondheidBijdrage aan periodiek

Doxepin cream is not effective in reducing itch in burn scar patients

Kwa, K A A; Legemate, C M; Pijpe, A; Meij-de Vries, A; Middelkoop, E; van Baar, M E; Breederveld, R S; Nieuwenhuis, M K (Functional Recovery And Quality Of Life After Burns)

OBJECTIVE: To evaluate the effect of doxepin hydrochloride 5% cream on reducing pruritus in burn scar patients compared to a placebo cream. METHOD: We conducted a multicenter triple-blind randomized clinical placebo-controlled crossover trial in which burn patients ≥18 years with an itch intensity ≥3 …

2020-03-01AlgemeenArtikel

Dutch Pancreatic Cancer Group. Cachexia, dietetic consultation, and survival in patients with pancreatic and periampullary cancer: A multicenter cohort study.

AEJ Latenstein; WPM Dijksterhuis; TM Mackay; S Beijer; CHJ van Eijck; IHJT de Hingh; IQ Molenaar; MGH van Oijen; HC van Santvoort; Marian de van der Schueren; J de Vos-Geelen; JHM de Vries; JW Wilmink; MG Besselink; HWM van Laarhoven

2020AlgemeenArtikel

Implementation of a Cost-Effective Physical Therapy Approach (Coach2Move) to Improve Physical Activity in Community-Dwelling Older Adults With Mobility Problems: Protocol for a Cluster-Randomized, Stepped Wedge Trial.

W. Heij; S. Teerenstra; L. Sweerts; Bart Staal; Ria Nijhuis-van der Sanden; T.J. Hoogeboom

BACKGROUND: Coach2Move is a personalized treatment strategy by physical therapists to elicit physical activity in community-dwelling older adults with mobility problems. OBJECTIVE: The primary objective of this study is to assess the effectiveness and cost-effectiveness of the implementation of Coach2Move …

2020AlgemeenArtikel

Mobile Health App (AGRIPPA) to Prevent Relapse After Successful Interdisciplinary Treatment for Patients With Chronic Pain: Protocol for a Randomized Controlled Trial

Stefan Elbers (Onderzoeker); Jan Pool (Onderzoeker); Harriët Wittink (Lector); Albere Köke (Onderzoeker); Else Scheffer (Onderzoeker); Rob Smeets (Onderzoeker)

Background: To facilitate adherence to adaptive pain management behaviors after interdisciplinary multimodal pain treatment, we developed a mobile health app (AGRIPPA app) that contains two behavior regulation strategies. Objective: The aims of this project are (1) to test the effectiveness of the AGRIPPA …

2020GezondheidArtikel

Improving Decision Making in Larynx Cancer by Developing a Decision Aid: A Mixed Methods Approach

Petersen, Japke F.; Berlanga, Adriana; Stuiver, Martijn M. (Faculteit Gezondheid); Hamming-Vrieze, Olga; Hoebers, Frank; Lambin, Philippe; van den Brekel, Michiel W.M.

OBJECTIVE: Patients diagnosed with advanced larynx cancer face a decisional process in which they can choose between radiotherapy, chemoradiotherapy, or a total laryngectomy with adjuvant radiotherapy. Clinicians do not always agree on the best clinical treatment, making the decisional process for patients …

2019-12AlgemeenArtikel

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