Objectives Chronic systemic low grade inflammation is associated with the age-related loss of muscle mass. Resistance exercise has been suggested to reduce or lower chronic systemic low grade inflammation. However, systemic chronic low-grade inflammation may adversely affect the adaptive response to …

Frailty is a complex phenomenon which is a result of a decline in reserve capacity. Although it is generally known that movement has a positive influence on a diversity of health outcomes in relatively healthy elderly, the effect on frail elderly is less known. Key elements in the clinical manifestation …

The world population is ageing rapidly. As society ages, the incidence of physical limitations is dramatically increasing, which reduces the quality of life and increases healthcare expenditures. In western society, ~30% of the population over 55 years is confronted with moderate or severe physical limitations. …

The purpose of these systematic review and meta-analysis was to assess the effectiveness of dairy components on nutritional status and physical fitness in older adults, as evidence for efficacy of the supplementation of these components is inconclusive. Scopus and MEDLINE were searched. Main inclusion …

INTRODUCTION: Minerals may contribute to prevent and treat sarcopenia, the age-related loss of muscle mass, muscle strength, and physical performance. So far, there is no comprehensive review on the impact of minerals on sarcopenia outcomes. The aim of this systematic review is to evaluate the role of …

The Dutch population is aging. Aging is associated with low muscle mass, strength and function, also known as sarcopenia. Sarcopenia leads to several problems as falling more often, physical frailty, disability and a higher risk of mortality. Additionally, absorption of many nutrients decreases with …

Goal: The goal of this thesis is to study the association between protein intake and the change in lean mass during a cutting and a bulking phase. The term cutting means being in a caloric deficit for a period of time to reduce the amount of body fat and maintain as much muscle mass as possible. The …

Background: Aging is accompanied by a progressive loss of muscle mass and muscle strength, also called sarcopenia. Adequate protein intake and distribution influences myofibrillar protein synthesis (MPS) and might therefore be important in the prevention of sarcopenia. Whether the daily amount and distribution …

Introduction According to the world health organization the number of older people is increasing. The number of older adults aged from 60 and beyond will be doubled in 2050 to 22% of the world’s population. Ageing is associated with involuntary loss of muscle mass, strength and physical function. This …

Introduction The Dutch Central Bureau of Statistics (CBS) predicts there will be 4,6 million people aged 65 years and older living in the Netherlands in 2040. As our life expectancy rises, so do age-related health problems, chronic diseases and co-morbidities. Age-related decline in muscle mass and strength …