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Physical Fitness and Chemotherapy Tolerance in Patients with Early-Stage Breast Cancer

Groen, Wim G.; Naaktgeboren, Willeke R.; van Harten, Wim H.; van Vulpen, Jonna K.; Kool, Nathalie (Faculteit Gezondheid); Sonke, Gabe S.; van der Wall, Elsken; Velthuis, Miranda J.; Aaronson, Neil K.; May, Anne M.; Stuiver, Martijn M. (Lectoraat Functioneel Herstel Bij Kanker)

INTRODUCTION: An optimal relative dose intensity (RDI) of adjuvant chemotherapy is associated with better survival in patients with breast cancer. Little is known about the role of physical fitness in attaining an adequate RDI in patients with early stage breast cancer. We investigated the association …

2022-04AlgemeenArtikelOpen Access

Characteristics of Participants and Nonparticipants in a Blended Internet-Based Physical Activity Trial for Breast and Prostate Cancer Survivors: Cross-sectional Study

vd Wiel, Hester J; Stuiver, Martijn M (Lectoraat Functioneel Herstel Bij Kanker); May, Anne M; van Grinsven, Susan; Benink, Marlou F A; Aaronson, Neil K; Oldenburg, Hester S A; van der Poel, Henk G; van Harten, Wim H; Groen, Wim G

BACKGROUND: As the number of cancer survivors is increasing, it is important to be able to offer exercise and physical activity (PA)-promoting interventions that are both effective and reasonably accessible. Internet-based interventions are typically less expensive and more accessible alternatives to …

2021-10AlgemeenArtikelOpen Access

Efficacy of Physical Exercise to Offset Anthracycline‐Induced Cardiotoxicity: A Systematic Review and Meta‐Analysis of Clinical and Preclinical Studies

Naaktgeboren, Willeke R.; Binyam, David; Stuiver, Martijn M. (Lectoraat Functioneel Herstel Bij Kanker); Aaronson, Neil K.; Teske, Arco J.; van Harten, Wim H.; Groen, Wim G.; May, Anne M.

Background Physical exercise is an intervention that might protect against doxorubicin‐induced cardiotoxicity. In this meta‐analysis and systematic review, we aimed to estimate the effect of exercise on doxorubicin‐induced cardiotoxicity and to evaluate mechanisms underlying exercise‐mediated cardioprotection …

2021-09-07AlgemeenAndersoortig materiaalOpen Access

Moderators of exercise effects on cancer-related fatigue

van Vulpen, Jonna K; Sweegers, Maike G; Peeters, Petra H M; Courneya, Kerry S; Newton, Robert U; Aaronson, Neil K; Jacobsen, Paul B; Galvão, Daniel A; Chinapaw, Mai J; Steindorf, Karen; Irwin, Melinda L; Stuiver, Martijn M (Urban Vitality); Hayes, Sandi; Griffith, Kathleen A; Mesters, Ilse; Knoop, Hans; Goedendorp, Martine M; Mutrie, Nanette; Daley, Amanda J; McConnachie, Alex; Bohus, Martin; Thorsen, Lene; Schulz, Karl-Heinz; Short, Camille E; James, Erica L; Plotnikoff, Ronald C; Schmidt, Martina E; Ulrich, Cornelia M; van Beurden, Marc; Oldenburg, Hester S; Sonke, Gabe S; van Harten, Wim H; Schmitz, Kathryn H; Winters-Stone, Kerri M; Velthuis, Miranda J; Taaffe, Dennis R; van Mechelen, Willem; Kersten, Marie José; Nollet, Frans; Wenzel, Jennifer; Wiskemann, Joachim; Verdonck-de Leeuw, Irma M; Brug, Johannes; May, Anne M; Buffart, Laurien M

PURPOSE: Fatigue is a common and potentially disabling symptom in patients with cancer. It can often be effectively reduced by exercise. Yet, effects of exercise interventions might differ across subgroups. We conducted a meta-analysis using individual patient data of randomized controlled trials (RCTs) …

2020-02AlgemeenArtikelClosed Access

Effect of physical exercise on cognitive function and brain measures after chemotherapy in patients with breast cancer (PAM study): protocol of a randomised controlled trial

Witlox, Lenja; Schagen, Sanne B; de Ruiter, Michiel B; Geerlings, Mirjam I; Peeters, Petra H M; Koevoets, Emmie W; van der Wall, Elsken; Stuiver, Martijn (Lectoraat Functioneel Herstel Bij Kanker); Sonke, Gabe; Velthuis, Miranda J; Palen, Job A M van der; Jobsen, Jan J; May, Anne M; Monninkhof, E M

INTRODUCTION: After treatment with chemotherapy, many patients with breast cancer experience cognitive problems. While limited interventions are available to improve cognitive functioning, physical exercise showed positive effects in healthy older adults and people with mild cognitive impairment. The …

2019-06AlgemeenArtikelOpen Access

Targeting Exercise Interventions to Patients With Cancer in Need: An Individual Patient Data Meta-Analysis

Buffart, Laurien M; Sweegers, Maike G; May, Anne M; Chinapaw, Mai J; van Vulpen, Jonna K; Newton, Rob U; Galvão, Daniel A; Aaronson, Neil K; Stuiver, Martijn M (Lectoraat Functioneel Herstel Bij Kanker); Jacobsen, Paul B; Verdonck-de Leeuw, Irma M; Steindorf, Karen; Irwin, Melinda L; Hayes, Sandi; Griffith, Kathleen A; Lucia, Alejandro; Herrero-Roman, Fernando; Mesters, Ilse; van Weert, Ellen; Knoop, Hans; Goedendorp, Martine M; Mutrie, Nanette; Daley, Amanda J; McConnachie, Alex; Bohus, Martin; Thorsen, Lene; Schulz, Karl-Heinz; Short, Camille E; James, Erica L; Plotnikoff, Ronald C; Arbane, Gill; Schmidt, Martina E; Potthoff, Karin; van Beurden, Marc; Oldenburg, Hester S; Sonke, Gabe S; van Harten, Wim H; Garrod, Rachel; Schmitz, Kathryn H; Winters-Stone, Kerri M; Velthuis, Miranda J; Taaffe, Dennis R; van Mechelen, Willem; José Kersten, Marie; Nollet, Frans; Wenzel, Jennifer; Wiskemann, Joachim; Brug, Johannes; Courneya, Kerry S

Background: Exercise effects in cancer patients often appear modest, possibly because interventions rarely target patients most in need. This study investigated the moderator effects of baseline values on the exercise outcomes of fatigue, aerobic fitness, muscle strength, quality of life (QoL), and self-reported …

2018-11AlgemeenAndersoortig materiaalClosed Access

Design of the SHAPE-2 study: the effect of physical activity, in addition to weight loss, on biomarkers of postmenopausal breast cancer risk

Willemijn A.M. van Gemert; Tim Takken; Anne M. May; Harriët Wittink (Lector); Albertine J. Schuit; Job van der Palen; Petra H.M. Peeters; Evelyn M. Monninkhof; Wouter B. Veldhuis; Jolijn I. Iestra

Background: Physical inactivity and overweight are two known risk factors for postmenopausal breast cancer. Former exercise intervention studies showed that physical activity influences sex hormone levels, known to be related to postmenopausal breast cancer, mainly when concordant loss of body weight …

2013GezondheidArtikelClosed Access

Effects of cancer rehabilitation on problem-solving, anxiety and depression

Korstjens, Irene; Mesters, Ilse; May, Anne M; van Weert, Ellen; van den Hout, Johanna H C; Ros, Wynand; Hoekstra-Weebers, Josette E H M; van der Schans, Cees (Healthy Ageing, Allied Health Care And Nursing); van den Borne, Bart

We tested the effects on problem-solving, anxiety and depression of 12-week group-based self-management cancer rehabilitation, combining comprehensive physical training (PT) and cognitive-behavioural problem-solving training (CBT), compared with PT. We expected that PT + CBT would outperform PT in improvements …

2011-05-01AlgemeenArtikelClosed Access

Cancer-related fatigue and rehabilitation

van Weert, Ellen; May, Anne M; Korstjens, Irene; Post, Wendy J; van der Schans, Cees (Healthy Ageing, Allied Health Care And Nursing); van den Borne, Bart; Mesters, Ilse; Ros, Wynand J G; Hoekstra-Weebers, Josette E H M

BACKGROUND: Research suggests that cancer rehabilitation reduces fatigue in survivors of cancer. To date, it is unclear what type of rehabilitation is most beneficial. OBJECTIVE: This randomized controlled trial compared the effect on cancer-related fatigue of physical training combined with cognitive …

2010-10-01AlgemeenArtikelClosed Access

Monitoring training progress during exercise training in cancer survivors

May, Anne M; van Weert, Ellen; Korstjens, Irene; Hoekstra-Weebers, Josette E; van der Schans, Cees (Healthy Ageing, Allied Health Care And Nursing); Zonderland, Maria L; Mesters, Ilse; van den Borne, Bart; Ros, Wynand J

OBJECTIVE: To examine the use of a submaximal exercise test in detecting change in fitness level after a physical training program, and to investigate the correlation of outcomes as measured submaximally or maximally. DESIGN: A prospective study in which exercise testing was performed before and after …

2010-03-01AlgemeenArtikelOpen Access

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