Prevention of non-communicable diseases through, among other factors, increasing vegeta bles and fruit (V&F) intake is a cost-effective strategy for risk reduction but requires behavioral change. Such changes in adolescents benefit from their active involvement. The Food Boost Challenge (FBC) was developed …

Background The ROS1 G2032R mutation is the most common on-target resistance mutation in crizotinib treated ROS1-positive lung cancer patients. The aim of our study was to investigate resistance mechanisms in SCL34A2-ROS1G2032R positive Ba/F3 cells against second line treatment with lorlatinib. Methods …

Dit rapport biedt een diepgaand inzicht in de belangrijke rol die de kinderopvang speelt in de eerste 1000 dagen van een kind's leven. Deze periode, die begint vóór de geboorte en duurt tot het kind twee jaar oud is, vormt de essentiële basis voor de biologische, sociale, motorische en cognitieve ontwikkeling …

Hoe kunnen we met een afnemend aantal logopedisten toch voldoende zorg voor communicatie en slikken blijven bieden? Creëer een rimpeleffect! Dan train je andere professionals, die met onze doelgroepen werken, om ondersteuning in communicatie en veilig slikken te bieden. Hoe kan praktijkgericht onderzoek …

The retirement phase is an opportunity to integrate healthy (nutrition/exercise) habits into daily life. We conducted this systematic review to assess which nutrition and exercise interventions most effectively improve body composition (fat/muscle mass), body mass index (BMI), and waist circumference …

Oil extraction from Andean lupin beans (Lupinus mutabilis SWEET) via supercritical carbon dioxide (scCO2) was studied on both lab scale and pilot scale. On the lab scale, the effect of pressure, solvent-to-feed ratio (S/F), sample particle size and temperature on oil yield were evaluated. The oil quality …

Blockchains draw everything they touch into a market logic. Is resistance possible?Activist and artistic engagements with blockchain technology point to (at least) threedifferent sets of tactics that aim to subvert this affordance of the technology. The firstis part of an accellerationist logic: riding …

This study is based on research focused on the importance of values in marketing communication. It looks into the effects of self-transcendent values as used by purpose brands, in comparison to self-enhancement values. In this context, values are important life goals on which the attitudes and actions …

Naar schatting telt Nederland anderhalf miljoen mensen die willen én kunnen werken, maar niet aan de slag zijn. Tegelijkertijd is er onder werkgevers grote behoefte aan arbeidskrachten. Een mismatch blijft bestaan. Het is tijd om ons perspectief op de arbeidsmarkt om te draaien: niet de mensen, maar …

Background Fluid therapy is a common intervention in critically ill patients. It is increasingly recognised that deresuscitation is an essential part of fluid therapy and delayed deresuscitation is associated with longer invasive ventilation and length of intensive care unit (ICU) stay. However, optimal …