Atrial fibrillation (AF) is the most common clinical tachyarrhythmia associated with significant morbidity and mortality and is expected to affect approximately 30 million North Americans and Europeans by 2050. AF is a persistent disease, caused by progressive, often age-related, derailment of proteostasis …

Samenvatting Doel van het onderzoek in het kader van de opleiding tot Master SEN is te komen tot een concreet advies voor de verbetering van de aanpak van de drugsproblematiek die speelt bij cliënten van Maatman Zorggroep. Maatman Zorggroep is de organisatie waar ik werkzaam ben als ambulante begeleider. …

It seems today that the streets in Mexico are littered with bodies of journalists. Since the ruling president, Felipe Calderón, declared war on drug cartels in December 2006, more than 30 journalists have been murdered or have gone missing. The escalating violence and attacks on Mexican media are emerging …

Binnen de verslavingszorg worden er verschillende vaardigheden aangeleerd om met trek om te gaan. Deze hunkering naar drugs of alcohol is nog steeds aanwezig als men gestopt is met gebruik van middelen. Trek kan op elk moment optreden door gewoonte en klassiek geconditioneerde cues. Gedurende trek is …

The South Caucasus compromises the states of Georgia, Armenia and Azerbaijan. It is a volatile region, distressed by ethno political conflicts which erupted after the fall of the powerful USSR. Free from Russian domination, the peoples of the South Caucasus - Armenians, Azerbaijanis and Georgians - started …

Hoofdstuk in Progression in forensic Psychiatry: About Boundaries van prof. mr. Marc Groenhuijsen en prof. dr. T.I. Oei. As a young adolescent the man started using soft drugs and as a result was expelled from school. Following a registration with RIAGG he was placed in a children’s home for some years. …

Falls are a major health problem in nursing home residents with dementia. In nursing homes one-third of all falls results in an injury. In order to take tailor-made preventive measures in time, the fall risk profile of each individual nursing home resident should be periodically evaluated. A systematic …

Glucocorticoids (GCs), such as prednisolone (PRED), are widely prescribed anti-inflammatory drugs, but their use may induce glucose intolerance and diabetes. GC-induced beta cell dysfunction contributes to these diabetogenic effects through mechanisms that remain to be elucidated. In this study, we hypothesized …

BACKGROUND: Prednisolone and other glucocorticoids (GCs) are potent anti-inflammatory and immunosuppressive drugs. However, prolonged use at a medium or high dose is hampered by side effects of which the metabolic side effects are most evident. Relatively little is known about their effect on gene-expression …

Physiotherapists should take a primary role in relation to the prevention and management of all diseases that are associated with low levels of physical activity. The benefits of regular physical activity on health, longevity, and well being easily surpass the effectiveness of any drugs or other medical …