The prevalence of obesity has almost tripled in the last four decades and is therefore an increasing threat to human health. Overnutrition – the excessive consumption of energy or nutrients, exceeding energy requirements – is believed to be one of the root causes of overweight and obesity. In literature, …

As the population is aging rapidly, there is a strong increase in the number of individuals with chronic disease and physical limitations. The decrease in skeletal muscle mass and function (sarcopenia) and the increase in fat mass (obesity) are important contributors to the development of physical limitations, …

People are designed to movePhysical activity, including regular exercise, leisure-time physical activity, active transport and regular sports activity, is the best way of staying physically and mentally fit and healthy, helps to tackle weight and obesity issues. In contrast, too much sitting and being …

Metformin prevents weight gain in patients with type 2 diabetes (T2D). However, the mechanisms involved are still unknown. In this post hoc analysis of the HOME trial, we aimed to determine whether metformin affects energy intake. Patients with T2D were treated with 850 mg metformin or received placebo …

Overweight and obesity are common in patients with facioscapulohumeral dystrophy (FSHD) and myotonic dystrophy type 1 (DM1). Lifestyle change is often challenging for patients with neuromuscular diseases, especially to increase physical activity. When lifestyle changes have not been effective, bariatric …

BACKGROUND: Overweight and obesity is a growing health problem worldwide. The most effective strategy to reduce weight is energy restriction (ER). ER has been shown to be beneficial in disease prevention and it reduces chronic inflammation. Recent studies suggest that reducing the protein quantity of …

A research protocol for emotional eaters

Obesity has become a major societal problem worldwide [1][2]. The main reason for severe overweight is excessive intake of energy, in relation to the individual needs of a human body. Obesity is associated with poor eating habits and/or a sedentary lifestyle. A significant part of the obese population …

From the thesis: "Summary Metabolic diseases that are characterized by a disturbance in energy balance because of feeding behavior, such as obesity and anorexia are known to be a world-wide problem. A better understanding in central regulation of energy intake and metabolism could give more insight in …

There is a growing number of eHealth interventions aiming at enhancing lifestyle to address obesity. However, the existing interventions do not take the emotional aspects of obesity into account. Forty percent of the overweight population is an emotional eater. Emotional eaters gain weight because of …