When treating cancer by radiation therapy it is always the goal to irradiate the tumour as much as possible and to spare the healthy tissue around it. For this a new type of radiation therapy called Volumetric Modulated ARC Therapy (VMAT) has been developed. During VMAT treatment the radiation machine …

Exposures to ionizing radiation frommedical examinations are on the rise. An important cause for this has been the advent and ever-increasing use of computed tomography (CT) scans for diagnostic purposes. It is often implied that population aging contributes significantly to this rise. Here, the trends …

Synthetic glucocorticoids are potent anti-inflammatory drugs but show dose-dependent metabolic side effects such as the development of insulin resistance and obesity. The precise mechanisms involved in these glucocorticoid-induced side effects, and especially the participation of adipose tissue in this …

The contribution of specific psychotropic drugs to fall risk in patients with dementia has not been quantified precisely until now. The authors evaluated the dose‐response relationship between psychotropic drugs and falls in nursing home residents with dementia. Daily drug use and daily falls were recorded …

PURPOSE: Advanced radiotherapy treatments require appropriate quality assurance (QA) to verify 3D dose distributions. Moreover, increase in patient numbers demand efficient QA-methods. In this study, a time efficient method that combines model-based QA and measurement-based QA was developed; i.e., the …

OBJECTIVE: Periodontitis, mostly associated with Porphyromonas gingivalis, has frequently been related to adverse pregnancy outcomes. We therefore investigated whether lipopolysaccharides of P. gingivalis (Pg-LPS) induced pregnancy complications in the rat. METHODS: Experiment 1: pregnant rats (day 14) …

The treatment of tumours in cancer patients have become more advanced and thus more complex. The verification of the dose distribution, calculated by clinical physicists, have thus become more complicated. VSL has started the development on measurements of absolute dose distributions in an antrhopomorphic …

PURPOSE: The aim of the present study was to investigate and compare coaches' and players' perceptions of training dose for a full competitive season. METHODS: Session Rating of Perceived Exertion (session-RPE), duration and training load (session-RPE * duration) of 33 professional soccer players (height …

Glucocorticoids (GCs) such as prednisolone are potent immunosuppressive drugs but suffer from severe adverse effects, including the induction of insulin resistance. Therefore, development of so-called Selective Glucocorticoid Receptor Modulators (SGRM) is highly desirable. Here we describe a non-steroidal …

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Patients treated with selective serotonin re‐uptake inhibitors (SSRIs) have been shown to have an increased risk of falling. In nursing homes, many patients with dementia are given SSRIs as a treatment for depression. In this group, however, the possible risk …