Introduction: To reduce continuously increasing costs in drug development, adverse effects of drugs need to be detected as early as possible in the process. In recent years, compound-induced gene expression profiling methodologies have been developed to assess compound toxicity, including Gene Ontology …

In 2005,one of Schering-Plough's core products- Clarityne was approved by the Chinese State Food Drugs Administration (SDFA) from prescription pharmaceutical to OTC drug in the Chinese market.Together with the increasing awareness of health care of the Chinese citizens, it gave a great chance to Schering-Plough …

Genomics has multiplied the number of targets for new therapeutic interventions, but this has not yet lead to a marked increase of pharma pipeline outputs. The complexity of protein function in higher order biological systems is often underestimated. Translation from in vitro and in vivo results to the …