a b s t r a c t: Objective: To study the impact of target volume changes in brain metastases during fractionated stereotactic radiosurgery (fSRS) and identify patients that benefit from MRI guidance. Material and methods: For 15 patients (18 lesions) receiving fSRS only (fSRSonly) and 19 patients (20 …

Background: In their research reports, scientists are expected to discuss limitations that their studies have. Previous research showed that often, such discussion is absent. Also, many journals emphasize the importance of avoiding overstatement of claims. We wanted to see to what extent editorial handling …

Introduction: Patients with kinesiophobia (fear of movement) avoid physical activity. Avoidance of physical activity is linked to adverse cardiac events and thus needs to be targeted. However, there is no contemporary measurement tool to assess kinesiophobia in cardiac patients. Therefore data on prevalence …

BACKGROUND: To evaluate whether a training programme is a feasible approach to facilitate occupational health professionals' (OHPs) use of knowledge and skills provided by a guideline. METHODS: Feasibility was evaluated by researching three aspects: 'acceptability', 'implementation' and 'limited efficacy'. …

This study aimed to get more insight into the spatial distribution pattern of the macrobenthos at the Vlakte van de Raan in relation to environmental gradients (median grain size, salinity and bathymetry). 82 samples were collected in November 2016 with a Van Veen grab using the research vessel the ‘RV …

Background: Computer-based cognitive rehabilitation is used to improve cognitive functioning after stroke. However, knowledge on adherence rates of stroke patients is limited. Objective: To describe stroke patients’ adherence with a brain training program using two frequencies of health professionals’ …

INTRODUCTION: While prone positioning (PP) has been shown to improve patient survival in moderate to severe acute respiratory distress syndrome (ARDS) patients, the rate of application of PP in clinical practice still appears low. AIM: This study aimed to determine the prevalence of use of PP in ARDS …

Introduction: Intractable epilepsy can be treated with the Ketogenic diet (KD). One of the side-effects of the KD is poor bone health. Experience from the Erasmus MC Sophia Children’s Hospital (EMCS) shows that the status of bone mineral density (BMD) is unknown in many cases. This makes it difficult …

Background & aim The aim of this study was to describe a decrease in resting energy expenditure during weight loss that is larger than expected based on changes in body composition, called adaptive thermogenesis (AT), in overweight and obese older adults. Methods Multiple studies were combined to assess …

Background: Despite improvement of tumour response rates in patients with progressive and metastatic cancer, immune checkpoint inhibitors (ICM) induce toxicities in cancer patients. Viscum album L. (VA, mistletoe) extracts are applied as add-on cancer therapy especially in German speaking countries and …