RNA metabolism is governed by RNA-binding proteins (RBPs), which regulate gene expression in cells, including immune system cells. Cells overcome stressing factors to ensure survival by employing a wide range of mechanisms that mitigate damage and restore homeostasis. One of the mechanisms is the formation …

The gram-positive bacterium Bacillus subtilis is widely used for enzyme production, especially due to its superior protein secretion capacity. In this study, we have investigated how efficient transcriptome analysis can identify general and protein-specific secretion stress. For this, we constructed …

OBJECTIVES:  To counteract sarcopenia in non-Western migrant older adults, lifestyle interventions with increased physical activity and adequate dietary protein intake are promising. However, regular community-based lifestyle interventions often lack a culture-sensitive approach. The aim of this study …

This study examines the role of host inflammation in the high mortality of tuberculous meningitis (TBM) and identifies potential biomarkers associated with improved survival. We conducted a case-control study involving 131 patients in a discovery cohort, 81 TBM patients in a validation cohort, and 43 …

Purpose The Optimal Physical Recovery After Hospitalization (OPRAH) Intervention is a blended intervention, combining a smartphone app for self-monitoring of physical activity and protein intake with coaching from a physiotherapist and dietician, to enhance the functional recovery after gastro-intestinal …

Objective Hemodialysis (HD) patients face challenges in upholding dietary compliance. This study aimed to compare dietary intake against disease-specific guidelines. Secondary, to assess the overall diet quality and to explore the association between dietary potassium intake and serum potassium concentrations. …

The increasing temperature of the past years has a negative impact on the agricultural sector. This is affecting crop growth negatively, as a result from the heat and drought stress the crops are experiencing. Moreover, the experienced heat and drought stress results in erosion of the soil, causing …

Background Standard care for older outpatients who are at risk of malnutrition in Indonesia is still based on the 2017’s recommendations of the Indonesian Geriatrics Society. and does not provide nutritional supplementation as recommended by ESPEN guidelines 2019/2022. Objective We compared the effects …

The antibiotic streptomycin is an integral part of cell culture medium. Because streptomycin inhibits bacterial protein synthesis, streptomycin might also have off-target effects on muscle cell function. Here, we studied the effect of streptomycin on C2C12 myoblasts, myofiber growth, and metabolism. …

Background The Optimal Physical Recovery After Hospitalization (OPRAH) Intervention is a blended intervention to enhance the functional recovery of patients who had gastro-intestinal or lung cancer surgery. Patients wore an activity tracker to monitor their physical activity and registered their protein …