BACKGROUND: T lymphocytes are orchestrators of adaptive immunity. Naïve T cells may differentiate into Th1, Th2, Th17 or iTreg phenotypes, depending on environmental co-stimulatory signals. To identify genes and pathways involved in differentiation of Jurkat T cells towards Th1 and Th2 subtypes we performed …

Single Fiber Reflectance spectroscopy (SFR) can be used to determine tissue optical properties such as scattering and absorption. The SFR technique employs a semi-empirical modal, which contains a parameter that is dependent on the fiber numerical aperture, NA . However, the NA is a wavelength dependent …

Carpal tunnel syndrome (CTS) is the most commonly diagnosed peripheral neuropathy due to entrapment. This syndrome is currently being diagnosed clinically, often confirmed through the use of neural conductivity studies (NCS). Over 25 percent of the cases are still missed using this method, while NCS …

UNLABELLED: Reaching movements are initiated by activity of the prime mover, i.e. the first activated arm muscle. We aimed to investigate the relationship between prime mover activity and kinematics of reaching in typically developing (TD) infants in supine and sitting position. Fourteen infants were …

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PURPOSE: Walking ability in general and specifically for lower limb amputees is of major importance for social mobility and ADL independence. Walking determines prosthesis prescription. The aim of this study was to mathematically analyse factors influencing claimed walking distance of lower limb amputees …

Elevated plantar foot pressures during gait in diabetic patients with neuropathy have been suggested to result, among other factors, from the distal displacement of sub-metatarsal head (MTH) fat-pad cushions caused by to claw/hammer toe deformity. The purpose of this study was to quantitatively assess …

The wrist allows the hand to combine dorsopalmar flexion and radioulnar deviation, a unique combination of functions that is made possible by a highly complex system of joints. The morphologic features of the carpal bones and of the radiocarpal and intercarpal contacts can be functionally interpreted …