The architecture of TP 53 , the most frequently mutated gene in human cancer, is more complex than previously thought. Using TP 53 variants as clinical biomarkers to predict response to treatment or patient outcome requires an unequivocal and standardized procedure toward a definitive strategy for the …

This article aims to contribute to skilful performance by reflecting on the importance of tacit knowing for practitioners who handle domestic violence in the field. Polanyi's insights on tacit knowing, skills and learning are applied to domestic violence cases and to reflections on approaches and …

Nowadays, modern societal trends and technologies enable us to live our lives with comfort and fun. On the one hand, these developments enhance quality of life, on the other hand there are downsides related to our health and happiness. Therefore, in our current society, it is necessary that parents consciously …

Over the past few years the terms 'fair trade', 'sustainable' and 'organic' have become more present in combination with tea products in the supermarkets. These terms are used for many different goals. Some suppliers actually try to provide the consumer with a product that has been produced following …

Waterschappen zijn overeengekomen met het Rijk om in 2020 de CO₂ - emissies met 30 procent te reduceren ten opzichte van 1990. (Europa decentraal, 2013) Het terugdringen van de energievraag van waterschappen staat lijnrecht tegenover een goed waterbeheer. Voor een goed waterbeheer moeten vele honderden …

Kverneland Group Nieuw-Vennep is an agricultural machinery manufacturer located in the town of Nieuw-Vennep in the Netherlands. In the spring of 2015 the company will start the production of a new generation of trailed field sprayers and the desire is to assemble these machines as quickly and efficiently …

Visualizing news is increasingly considered an apt way for dealing with two challenges of modern journalism: disclosing big data and presenting complex information in a way that is easy to comprehend. Newsrooms are trying their hand at it, and finding ways to organize the production of information visualizations …

In this paper we describe our work in progress on the development of a set of criteria to predict text difficulty in Sign Language of the Netherlands (NGT). These texts are used in a four year bachelor program, which is being brought in line with the Common European Framework of Reference for Languages …

Discussions about the importance of the built environment for healthcare delivery extend at least as far back as Hippocrates 1 (400 BC). The iconic Florence Nightingale (1859) also strongly believed in the influence the indoor environment has on the progress of disease and recovery. Today, the role of …

In many countries the Eurasian otter (Lutra lutra) is extinct or numbers are declining; resulting in a classification as “near threatened” on the IUCN’s Red List. In one-third of the European countries, however, conservation efforts, enabled the return of the species or the improvement of weakened populations. …