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Prediction model to predict critical weight loss in patients with head and neck cancer during (chemo)radiotherapy

Langius, Jacqueline A.E.; Twisk, Jos; Kampman, Martine; Doornaert, Patricia; Kramer, Mark H.H.; Weijs, Peter J.M. (Lectoraat Voeding En Beweging); Leemans, C. René

OBJECTIVES: Patients with head and neck cancer (HNC) frequently encounter weight loss with multiple negative outcomes as a consequence. Adequate treatment is best achieved by early identification of patients at risk for critical weight loss. The objective of this study was to detect predictive factors …

2016-01AlgemeenArtikel

Development of an iterative reconstruction method to overcome 2D detector low resolution limitations in MLC leaf position error detection for 3D dose verification in IMRT

Visser, Ruurd; J., Godart; Wauben, D.J.L.; Langendijk, J.; van 't Veld, A.A.; Korevaar, E.W.

The objective of this study was to introduce a new iterative method to reconstruct multi leaf collimator (MLC) positions based on low resolution ionization detector array measurements and to evaluate its error detection performance. The iterative reconstruction method consists of a fluence model, a detector …

2016AlgemeenArtikel

Geometric changes of parotid glands caused by hydration during chemoradiotherapy

Simon R. van Kranen,; Sanne C. C. van Weerdenburg,; Peter Remeijer; Petronella M. Kager; Olga Hamming-Vrieze; Emmy Kuipers (Lid Lectoraat); Wilma D. Heemsbergen,; Suzanne van Beek,

Abstract: Plan adaptation during the course of (chemo)radiotherapy of H&N cancer requires repeat CT scanning to capture anatomy changes such as parotid gland shrinkage. Hydration, applied to prevent nephrotoxicity from cisplatin, could temporarily alter the hydrogen balance and hence the captured anatomy. …

2015-12-01GezondheidArtikel

Impact of tumour invasion on seminal vesicles mobility in radiotherapy of prostate cancer

Jelle Scheurleer (Lid Lectoraat); Monica van der Burgt; Laura Bergsma; Jeroen de Vries; Floris J. Pos; Robin Kalisvaart; Wilma Heemsbergen; Peter Remeijer; Uulke van der Heide

Abstract gepubliseerd in Elsevier: For patients with intermediate- and high risk prostate cancer, treated with high dose radiotherapy, the CTV generally involves the prostate and (part of) the seminal vesicles (SV) [1,2]. Fiducial markers locate the prostate reliably during radiotherapy [3]. However …

2015-10-20GezondheidArtikel

Calibration and validation of kv-CBCT in room imaging for dose calculation and adaptive radiotherapy

M. A. Palacios; M. Soumokil; T. S. Rosario

Op verzoek van Jelle Scheurleer: Purpose: To investigate the accuracy of dose calculation on cone beam CT (CBCT) data sets after HU-RED calibration and validation in phantom studies and clinical patients. Material and methods: Calibration of HU-RED curves for kV-CBCT were generated for three clinical …

2015-09-04GezondheidArtikel

Multicriteria optimization enables less experienced planners to efficiently produce high quality treatment plans in head and neck cancer radiotherapy

Kierkels, Roel G J; Visser, Ruurd; Bijl, Hendrik P; Langendijk, Johannes A; van 't Veld, Aart A; Steenbakkers, Roel J H M; Korevaar, Erik W

OBJECTIVES: To demonstrate that novice dosimetry planners efficiently create clinically acceptable IMRT plans for head and neck cancer (HNC) patients using a commercially available multicriteria optimization (MCO) system. METHODS: Twenty HNC patients were enrolled in this in-silico comparative planning …

2015-04-12AlgemeenArtikel

Evaluation of DVH-based treatment plan verification in addition to gamma passing rates for head and neck IMRT

Visser, Ruurd; Wauben, David J.L.; de Groot, Martijn; Steenbakkers, Roel J.H.M.; Godart, Jeremy; van 't Veld, Aart A.; Langendijk, Johannes A.; Korevaar, Erik W.; Bijl, Hendrik P

Background and purpose: Treatment plan verification of intensity modulated radiotherapy (IMRT) is generally performed with the gamma index (GI) evaluation method, which is difficult to extrapolate to clinical implications. Incorporating Dose Volume Histogram (DVH) information can compensate for this. …

2014-09-01AlgemeenArtikel

The impact of gastrointestinal and genitourinary toxicity on health related quality of life among irradiated prostate cancer patients

Schaake, Wouter (Healthy Ageing, Allied Health Care And Nursing); Wiegman, Erwin M.; de Groot, Martijn; van der Laan, Hans Paul; van der Schans, Cees; van den Bergh, Alfons C.M.; Langendijk, Johannes A.

PURPOSE: To determine the impact of late radiation-induced toxicity on health-related quality of life (HRQoL) among patients with prostate cancer. PATIENTS AND METHODS: The study sample was composed of 227 patients, treated with external beam radiotherapy. Common Terminology Criteria for Adverse Events …

2014-02-01AlgemeenArtikel

2nd Annual PhD student meeting of the Cancer Research Center Groningen

Schaake, Wouter

Quality of life among prostate cancer survivors:a longitudinal population based study. Purpose To investigate the course of quality of life (QoL) among prostate cancer patients treated with external beam radiotherapy and to compare the results with QoL of a normal age-matched reference population. Patients …

2014AlgemeenConferentiebijdrage

Quality of life among prostate cancer patients: a prospective longitudinal population-based study

Schaake, Wouter (Healthy Ageing, Allied Health Care And Nursing); de Groot, Martijn; Krijnen, Wim (Statistical Techniques For Applied Research); Langendijk, Johannes A.; van den Bergh, Alfons C.M.

Purpose To investigate the course of quality of life (QoL) among prostate cancer patients treated with external beam radiotherapy and to compare the results with QoL of a normal age-matched reference population. Conclusion Prostate cancer patients experience a small worsening of QoL as compared with …

2013-08-01Gezondheid; …Artikel

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