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Zocht je misschien: infections, intention?

Wound infection following implant removal of foot, ankle, lower leg or patella; a protocol for a multicenter randomized controlled trial investigating the (cost-)effectiveness of 2 g of prophylactic cefazolin compared to placebo (WIFI-2 trial)

Sanders, Fay R.K.; Penning, Diederick; Backes, Manouk; Dingemans, Siem A.; van Dieren, Susan; Eskes, Anne M. (Lectoraat Patiënt- En Familieparticipatie In De Klinische Zorg); Goslings, J. Carel; Kloen, Peter; Mathôt, Ron A.A.; Schep, Niels W.L.; Spijkerman, Ingrid J.B.; Schepers, Tim

Background: Elective implant removal (IR) after fracture fixation is one of the most common procedures within (orthopedic) trauma surgery. The rate of surgical site infections (SSIs) in this procedure is quite high, especially below the level of the knee. Antibiotic prophylaxis is not routinely prescribed, …

2021-12AlgemeenArtikel

Neuropsychological and psychosocial functioning of children with perinatal HIV-infection in The Netherlands

S.E.M. van Opstal; E.J. Dogterom; M.N. Wagener; F.K. Aarsen; H.S. Miedema; P.D.D.M. Roelofs; L.C. van der Knaap; P.L.A. Fraaij; K. Stol; A.B. Rietman; E.C.M. van Gorp; A.M.C. van Rossum; E.M.W.J. Utens

Advances in antiretroviral treatment improved the life expectancy of perinatally HIV-infected children. However, growing up with HIV provides challenges in daily functioning. This cross-sectional cohort study investigated the neuropsychological and psychosocial functioning of a group of perinatally HIV-infected …

2021-09-28GezondheidArtikel

SARS-CoV-2 infection in pregnancy during the first wave of COVID-19 in the Netherlands: a prospective nationwide population-based cohort study (NethOSS)

E.M. Overtoom; A.N. Rosman; J.J. Zwart; T.E. Vogelvang; T. van den Akker; K.W.M. Bloemenkamp

Objective To describe characteristics, risk factors and maternal, obstetric and neonatal outcomes of pregnant women infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Design Multi-centre prospective population-based cohort study. Setting Nationwide study in the Netherlands. Population Pregnant …

2021-09-08GezondheidArtikel

School functioning of children with perinatal HIV-infection in high-income countries: a systematic review

S.E.M. van Opstal; M.N. Wagener; H.S. Miedema; E.M.W.J. Utens; F.K. Aarsen; L.C. van der Knaap; E.C.M. van Gorp; A.M.C. van Rossum; P.D.D.M. Roelofs

Introduction Since the introduction of combination antiretroviral therapy, human immunodeficiency virus (HIV) infection is a manageable chronic disease. However, school-age children (4–18 years) living with HIV could still experience problems with functioning at school, due to the impact of the virus …

2021-06-04GezondheidArtikel

Poor nutritional status, risk of sarcopenia and nutrition related complaints are prevalent in COVID-19 patients during and after hospital admission

Wierdsma, Nicolette J.; Kruizenga, Hinke M.; Konings, Lotte AML.; Krebbers, Daphne; Jorissen, Jolein RMC.; Joosten, Marie-Helene I.; van Aken, Loes H.; Tan, Flora M.; van Bodegraven, Ad A.; Soeters, Maarten R.; Weijs, Peter JM. (Lectoraat Voeding En Beweging)

BACKGROUND AND AIMS: Patients with COVID-19 infection presents with a broad clinical spectrum of symptoms and complications. As a consequence nutritional requirements are not met, resulting in weight- and muscle loss, and malnutrition. The aim of the present study is to delineate nutritional complaints, …

2021-06-01AlgemeenArtikel

Sputum Proteome Signatures of Mechanically Ventilated Intensive Care Unit Patients Distinguish Samples with or without Anti-pneumococcal Activity

Seinen, Jolien; Engelke, Rudolf; Abdullah, Mohammed R; Voß, Franziska; Michalik, Stephan; Dhople, Vishnu M; Dieperink, Willem; de Smet, Anne Marie G A; Völker, Uwe; van Dijl, Jan Maarten; Schmidt, Frank; Hammerschmidt, Sven

Respiratory pathogens like Streptococcus pneumoniae can cause severe pneumonia. Nonetheless, mechanically ventilated intensive care patients, who have a high risk of contracting pneumonia, rarely develop pneumococcal pneumonia. Mechanically ventilated patients are at risk of contracting pneumonia. Therefore, …

2021-04-27AlgemeenArtikel

Pre-operative and post-operative recommendations to surgical wound care interventions

Gillespie, Brigid M.; Walker, Rachel M.; McInnes, Elizabeth Catherine; Moore, Zena; Eskes, Anne (Lectoraat Patiënt- En Familieparticipatie In De Klinische Zorg); O'Connor, Tom; Harbeck, Emma; White, Codi; Scott, Ian; Vermeulen, Hester; Chaboyer, Wendy P.

Background: The increasing numbers of surgeries involving high risk, multi-morbid patients, coupled with inconsistencies in the practice of perioperative surgical wound care, increases patients’ risk of surgical site infection and other wound complications. Objectives: To synthesise and evaluate the …

2021AlgemeenArtikel

Enterocytes, fibroblasts and myeloid cells synergize in anti-bacterial and anti-viral pathways with IL22 as the central cytokine

Jean Paul ten Klooster (Onderzoeker); Marianne Bol-Schoenmakers (Onderzoeker); Kitty van Summeren (Onderzoeker); Arno van Vliet (Onderzoeker); Cornelis de Haan (Onderzoeker); Frank van Kuppeveld (Onderzoeker); Saertje Verkoeijen (Onderzoeker); Raymond Pieters (Lector)

IL22 is an important cytokine involved in the intestinal defense mechanisms against microbiome. By using ileum-derived organoids, we show that the expression of anti-microbial peptides (AMPs) and anti-viral peptides (AVPs) can be induced by IL22. In addition, we identified a bacterial and a viral route, …

2021GezondheidArtikel

The Impact of COVID-19 from the Perspectives of Dutch District Nurses: a Mixed-Methods Study

Jessica D. Veldhuizen (Onderzoeker); Sandra Zwakhalen (Onderzoeker); Bianca M. Buurman (Onderzoeker); Nienke Bleijenberg (Lector)

Little is known about how COVID-19 affects older patients living at home or how it affects district nursing teams providing care to these patients. This study aims to (1) explore, from the perspectives of Dutch district nurses, COVID-19′s impact on patients receiving district nursing care, district nursing …

2021GezondheidArtikel

The impact of the COVID-19 pandemic on European police officers

Frenkel, Marie Ottilie; Giessing, Laura; Egger-Lampl, Sebastian; Hutter, Vana; Oudejans, Raoul R.D. (Faculteit Bewegen, Sport En Voeding); Kleygrewe, Lisanne; Jaspaert, Emma; Plessner, Henning

Purpose: Facing the COVID-19 pandemic, police officers are confronted with various novel challenges, which might place additional strain on officers. This mixed-method study investigated officers' strain over a three-month-period after the lockdown. Methods: In an online survey, 2567 police officers …

2021AlgemeenArtikel

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