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Pre-Participation Screenings Frequently Miss Occult Cardiovascular Conditions in Apparently Healthy Male Middle-Aged First-Time Marathon Runners

Laily, Inarota; Wiggers, Tom G.H.; Van Steijn, Niels; Bijsterveld, Nick; Bakermans, Adrianus J.; Froeling, Martijn; Van Den Berg-Faay, Sandra; De Haan, Ferdinand H. (Urban Vitality); De Bruin-Bon, Rianne H.A.C.M.; Boekholdt, S. Matthijs; Planken, R. Nils; Verhagen, Evert; Jorstad, Harald T.

Introduction: The optimal pre-participation screening strategy to identify athletes at risk for exercise-induced cardiovascular events is unknown. We therefore aimed to compare the American College of Sports Medicine (ACSM) and European Society of Cardiology (ESC) pre-participation screening strategies …

2024-06AlgemeenArtikel

Associations of individual chronic diseases and multimorbidity with multidimensional frailty

Robbert Gobbens (Lector); Sandra Kuiper; Henriëtte Dijkshoorn; Marcel A.L.M. van Assen

ABSTRACT Objective: To examine the associations between individual chronic diseases and multidimensional frailty comprising physical, psychological, and social frailty. Methods: Dutch individuals (N = 47,768) age ≥ 65 years completed a general health questionnaire sent by the Public Health Services …

2023-11-04GezondheidArtikel

Nailfold capillaroscopy and candidate-biomarker levels in systemic sclerosis-associated pulmonary hypertension

Lemmers, Jacqueline; van Caam, Arjan; Kersten, Brigit E.; van den Ende, Cornelia; Knaapen, Hanneke; van Dijk, Arie; Hagmolen of Ten Have, Wanda; van den Hoogen, Frank; Koenen, Hans J P M; van Leuven, Sander; Alkema, Wynand; Smeets, Ruben L; Vonk, Madelon C.

Objectives: Pulmonary hypertension is one of the leading causes of death in systemic sclerosis. Early detection and treatment of pulmonary hypertension in systemic sclerosis is crucial. Nailfold capillaroscopy microscopy, vascular autoantibodies AT1R and ETAR, and several candidate-biomarkers have the …

2023-05-22AlgemeenArtikel

The SMILE lifestyle intervention for people with a severe mental illness

Florine Walburg (Lid Lectoraat)

People with a ‘severe mental illness’ (SMI) are those who suffer from a psychiatric illness for a prolonged period of time that seriously affects their social functioning, professional functioning and functioning in the community, and who are in need of professional care or treatment. SMI is not limited …

2023-04-03GezondheidProefschrift

A Clinical Pharmacology and Therapeutics Teacher’s Guide to Race-Based Medicine, Inclusivity, and Diversity

Michiel J. Bakkum; Petra Verdonk; Elias G. Thomas; Floor van Rosse; Michael Okorie; Paraskevi Papaioannidou; Robert Likic; Emilio J. Sanz; Jelle Tichelaar (Lector)

The relationship between race and biology is complex. In contemporary medical science, race is a social construct that is measured via self-identification of study participants. But even though race has no biological essence, it is often used as variable in medical guidelines (e.g., treatment recommendations …

2022-10-23GezondheidArtikel

Intra-abdominal hypertension and abdominal compartment syndrome in patients admitted to the ICU

Smit, Marije; Koopman, Bart; Hulscher, Jan B F; Hofker, H Sijbrand; van Meurs, Matijs; Zijlstra, Jan G; Dieperink, Willem

BACKGROUND: Intra-abdominal hypertension is frequently present in critically ill patients and is an independent predictor for mortality. Risk factors for intra-abdominal hypertension and abdominal compartment syndrome have been widely investigated. However, data are lacking on prevalence and outcome …

2020-10-01AlgemeenArtikel

Associations of chronic illnesses and socio-demographic factors with health-related quality of life of older adults in Nigeria

Joel O. Faronbi; Aishat O. Ajadi; R.J.J. Gobbens (Lector)

Background: The increase in life expectancy has brought about a higher prevalence of chronic illnesses among older people. Objectives: To identify common chronic illnesses among older adults, to examine the influence of such conditions on their Health-Related Quality of Life (HRQoL), and to determine …

2020-09-03GezondheidArtikel

Fetal sex and maternal pregnancy outcomes

Broere-Brown, Zoe A; Adank, Maria C; Benschop, Laura; Tielemans, Myrte; Muka, Taulant; Gonçalves, Romy; Bramer, Wichor M; Schoufour, Josje D; Voortman, Trudy; Steegers, Eric A P; Franco, Oscar H; Schalekamp-Timmermans, Sarah

BACKGROUND: Since the placenta also has a sex, fetal sex-specific differences in the occurrence of placenta-mediated complications could exist. OBJECTIVE: To determine the association of fetal sex with multiple maternal pregnancy complications. SEARCH STRATEGY: Six electronic databases Ovid MEDLINE, …

2020-05-11AlgemeenAndersoortig materiaal

Effect of muscle alteration on long term survival in ischemic stroke patients

Akshay Biere (Student); Martijn Scheffer (Student); Patrick Schenkers (Begeleider); Peter Lesterhuis (Begeleider)

Patients who had an ischemic stroke have a poor life expectancy. To improve prognosis in ischemic stroke it is needed to discover additional prognostic biomarkers. This study investigated whether sarcopenia or myosteatosis affected long-term survival in ischemic stroke patients. The secondary aim was …

2020-01-30GezondheidBachelor

Associations Between Obesity and Multidimensional Frailty in Older Chinese People with Hypertension

Xiaoyue Song (Onderzoeker); Weihong Zhang (Onderzoeker); Cynthia Hallensleben (Onderzoeker); Anke Versluis (Onderzoeker); Rianne van der Kleij (Onderzoeker); Zongliang Jiang (Onderzoeker); Niels H Chavannes (Onderzoeker); Dr. R.J.J. Gobbens (Lector)

Purpose: To investigate the prevalence of multidimensional frailty in older people with hypertension and to examine a possible relationship of general obesity and abdominal obesity to frailty in older people with hypertension. Patients and Methods: A sample of 995 community-dwelling older people with …

2020GezondheidArtikel

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