Glucocorticoids (GCs) such as prednisolone are potent immunosuppressive drugs but suffer from severe adverse effects, including the induction of insulin resistance. Therefore, development of so-called Selective Glucocorticoid Receptor Modulators (SGRM) is highly desirable. Here we describe a non-steroidal …

Glucocorticoids (GCs), such as prednisolone (PRED), are widely prescribed anti-inflammatory drugs, but their use may induce glucose intolerance and diabetes. GC-induced beta cell dysfunction contributes to these diabetogenic effects through mechanisms that remain to be elucidated. In this study, we hypothesized …

Welke welzijnsrisico’s vormen de basis voor een monitoringsprotocol van konijnenwelzijn op de kinderboerderij? Is een voornamelijk diergericht monitoringsprotocol een bruikbaar instrument voor een welzijnsrisicoinventarisatie van konijnen op de kinderboerderij? Dit document bevat het achterliggend onderzoek …

In two covariation bias experiments, we investigated whether socially anxious women overestimate the contingency between social events and signs of rejection and/or to underestimate the contingency between social events and approval. Participants were exposed to descriptions of ambiguous or negative …