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Feasibility Study to Assess Canagliflozin Distribution and Sodium-Glucose Co-Transporter 2 Occupancy Using [18F]Canagliflozin in Patients with Type 2 Diabetes

van der Hoek, Sjoukje; Willemsen, Antoon T.M.; Visser, Ton; Heeres, Andre; Mulder, Douwe J.; Bokkers, Reinoud P.H.; Slart, Riemer H.J.A.; Elsinga, Philip H.; Heerspink, Hiddo J.L.; Stevens, Jasper

Sodium-glucose co-transporter 2 (SGLT2) inhibitors, including canagliflozin, reduce the risk of cardiovascular and kidney outcomes in patients with and without type 2 diabetes, albeit with a large interindividual variation. The underlying mechanisms for this variation in response might be attributed …

2023-03-10AlgemeenArtikel

Effectiveness of an intervention to reduce sedentary behaviour as a personalised secondary prevention strategy for patients with coronary artery disease: main outcomes of the SIT LESS randomised clinical trial

B.M.A. van Bakel; S.H. Kroesen; E.A. Bakker; R.V. van Miltenburg; A. Günal; W.R.M. Aengevaeren; F.F. Willems; R. Wondergem (Onderzoeker); M.F. Pisters (Lector); M. de Bruin; M.T.E. Hopman; D.H.J. Thijssen; T.M.H. Eijsvogels

Background A high sedentary time is associated with increased mortality risk. Previous studies indicate that replacement of sedentary time with light- and moderate-to-vigorous physical activity attenuates the risk for adverse outcomes and improves cardiovascular risk factors. Patients with cardiovascular …

2023-02-14GezondheidArtikel

The trajectory of nutritional Status and physical activity before and after transcatheter aortic valve implantation

van Erck, Dennis; Dolman, Christine D.; Scholte Op Reimer, Wilma J. M.; Henriques, José P.; Weijs, Peter J. M. (Lectoraat Voeding En Beweging); Delewi, Ronak; Schoufour, Josje D. (Lectoraat Voeding En Beweging)

It is suggested that older patients waiting for an elective surgical procedure have a poor nutritional status and low physical activity level. It is unknown if this hypothesis is true and if these conditions improve after a medical procedure. We aimed to determine the trajectory of both conditions before …

2022-12-02AlgemeenArtikel

Practice of Awake Prone Positioning in Critically Ill COVID–19 Patients––insights from the PRoAcT–COVID study

Stilma, W. (Faculteit Gezondheid); Valk, C.; Van Meenen, D.; Schultz, M.; Paulus, F. (Lectoraat Critical Care)

Introduction It is unknown how awake prone positioning was practiced in patients with COVID–19 in the second wave of the national outbreak in the Netherlands. Objectives We studied the practice of awake prone positioning in COVID–19 patients admitted to the ICU because of acute hypoxemic respiratory …

2022-10-24AlgemeenConferentiebijdrage

An appeal to our government for nationwide policies in the prevention of cardiovascular disease

van Trier, T. J.; Mohammadnia, N.; Snaterse, M. (Faculteit Gezondheid); Peters, R. J. G.; Jørstad, H. T.; Bax, W. A.; Mackenbach, J. D.

The high prevalence and burden of cardiovascular diseases (CVD) is largely attributable to unhealthy lifestyle factors such as smoking, alcohol consumption, physical inactivity and unhealthy food habits. Prevention of CVD, through the promotion of healthy lifestyles, appears to be a Sisyphean task for …

2022AlgemeenAndersoortig materiaal

The effect of a multidisciplinary lifestyle program for patients with rheumatoid arthritis, an increased risk for rheumatoid arthritis or with metabolic syndrome-associated osteoarthritis

Walrabenstein, Wendy; van der Leeden, Marike; Weijs, Peter (Lectoraat Voeding En Beweging); van Middendorp, Henriët; Wagenaar, Carlijn; van Dongen, Johanna Maria; Nieuwdorp, Max; de Jonge, Catharina Sophia; van Boheemen, Laurette; van Schaardenburg, Dirkjan

Low-grade inflammation and metabolic syndrome are seen in many chronic diseases, including rheumatoid arthritis (RA) and osteoarthritis (OA). Lifestyle interventions which combine different non-pharmacological therapies have shown synergizing effects in improving outcomes in patients with other chronic …

2021-10-18AlgemeenArtikel

Cardiorespiratory fitness and physical activity in people who have rheumatoid arthritis at an increased risk of cardiovascular disease

Sobejana, M.; van den Hoek, J. (Hogeschool Van Amsterdam); Metsios, G. S.; Kitas, G. D.; Jorstad, H. T.; van der Leeden, M.; Pijnappels, M.; Lems, W. F.; Nurmohamed, M. T.; van der Esch, M. (Lectoraat Interdisciplinaire Zorg Voor Chronische Gewrichtsaandoeningen)

Lower cardiorespiratory fitness (CRF) and physical activity (PA) associate with higher cardiovascular disease (CVD) risk, but the relationship between CRF and PA in people who have rheumatoid arthritis (RA) at an increased CVD risk (CVD-RA) is not known. The objectives of this study were to determine …

2021-07-31AlgemeenArtikel

Active Ingredients and Mechanisms of Change in Motivational Interviewing for Smoking Cessation in Patients With Coronary Artery Disease

Jos Dobber (Lid Lectoraat); Marjolein Snaterse; Corine Latour; Ron Peters; Gerben ter Riet; Wilma Scholte op Reimer; Lieuwe de Haan; B.K.G. (Berno) van Meijel (Lector)

Background: For patients with coronary artery disease (CAD), smoking is an important risk factor for the recurrence of a cardiovascular event. Motivational interviewing (MI) may increase the motivation of the smokers to stop smoking. Data on MI for smoking cessation in patients with CAD are limited, …

2021-06-22GezondheidArtikel

The influence of partners on successful lifestyle modification in patients with coronary artery disease

Verweij, Lotte; Jørstad, Harald T.; Minneboo, Madelon; ter Riet, Gerben; Peters, Ron J.G.; Scholte op Reimer, Wilma J.M.; Snaterse, Marjolein (Lectoraat Geïntegreerde Complexe Zorg)

Background: Marital status is associated with prognosis in patients with cardiovascular disease (CVD).However, the influence of partners on successful modification of lifestyle-related risk factors (LRFs) in secondaryCVD prevention is unclear. Therefore, we studied the association between the presence …

2021-06-01AlgemeenArtikel

Active Ingredients and Mechanisms of Change in Motivational Interviewing for Smoking Cessation in Patients With Coronary Artery Disease: A Mixed Methods Study

Dobber, Jos; Snaterse, Marjolein (Lectoraat Geïntegreerde Complexe Zorg); Latour, Corine (Urban Vitality); Peters, Ron; ter Riet, Gerben; Scholte op Reimer, Wilma; de Haan, Lieuwe; van Meijel, Berno

2021-06AlgemeenArtikel

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