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Magnesium prevents vascular calcification in Klotho deficiency

Alkema, Wynand

Klotho knock-out mice are an important model for vascular calcification, which is associated with chronic kidney disease. In chronic kidney disease, serum magnesium inversely correlates with vascular calcification. Here we determine the effects of serum magnesium on aortic calcification in Klotho knock-out …

2020-03-01AlgemeenArtikel

De betrouwbaarheid van de Philips VISIQ

Ingrid Kirsten Jellema (Student); Indy Timmer (Student); Ruurd Visser (Begeleider); Janine Baër (Begeleider)

Het doel van deze studie is bepalen in hoeverre metingen van het handheld echografietoestel, de Philips VISIQ, verschillen met die van een conventioneel echografietoestel bij het meten van de diameter van de aorta abdominalis. Uit het onderzoek is gebleken dat de Philips VISIQ de abdominale aortadiameter, …

2020-01-08GezondheidBachelor

Validation of the Systematic COronary Risk Evaluation - Older Persons (SCORE-OP) in the EPIC-Norfolk prospective population study

Verweij, Lotte; Peters, Ron J. G.; Scholte op Reimer, Wilma J.M.; Boekholdt, Matthijs S.; Luben, Robert M.; Wareham, Nicholas J.; Khaw, Kay-Tee; Latour, Corine H.M. (Urban Vitality); Jorstad, Harald T.

BACKGROUND: The Systematic COronary Risk Evaluation - Older Persons (SCORE-OP) algorithm is developed to assess 10-year risk of death due to cardiovascular disease (CVD) in individuals aged ≥65 years. We studied the performance of SCORE-OP in the European Prospective Investigation of Cancer Norfolk (EPIC-Norfolk) …

2019-10-15AlgemeenArtikel

CT determined psoas muscle area predicts mortality in women undergoing transcatheter aortic valve implantation

van Mourik, Martijn S.; Janmaat, Yvonne C.; van Kesteren, Floortje; Vendrik, Jeroen; Planken, R. Nils; Henstra, Marieke J.; Velu, Juliëtte F.; Vlastra, Wieneke; Zwinderman, Aeilko H.; Koch, Karel T.; de Winter, Robbert J.; Wykrzykowska, Joanna J.; Piek, Jan J.; Henriques, José P.S.; Lanting, Vincent R.; Baan, Jan; Latour, Corine (Urban Vitality); Lindeboom, Robert; Vis, M. Marije

Objectives: The aim of this study was to assess the predictive value of PMA measurement for mortality. Background: Current surgical risk stratification have limited predictive value in the transcatheter aortic valve implantation (TAVI) population. In TAVI workup, a CT scan is routinely performed but …

2019-03-01AlgemeenAndersoortig materiaal

Usefulness of cardiopulmonary exercise testing to predict the development of arterial hypertension in adult patients with repaired isolated coarctation of the aorta.

Alexander Van de Bruaene; Jan Müller; Werner Budts; Luc Vanhees (Lector); Alessandro Giardini; Rosalien Buys; Sachin Khambadkone; Veronique Cornelissen

BACKGROUND: Patients who underwent surgery for aortic coarctation (COA) have an increased risk of arterial hypertension. We aimed at evaluating (1) differences between hypertensive and non-hypertensive patients and (2) the value of cardiopulmonary exercise testing (CPET) to predict the development or …

2013GezondheidArtikel

Production of plasminogen activators and inhibitor by serially propagated endothelial cells from adult human blood vessels

van Hinsbergh, V W; Binnema, D; Scheffer, M A; Sprengers, E D; Kooistra, T; Rijken, D C

Endothelial cells were isolated from arteries and veins obtained from elderly people at autopsy and propagated for 37 to 69 population doublings. The cells secreted tissue-type plasminogen activator (t-PA) and PA inhibitor-1, and, after subculturing, urokinase-type PA (u-PA) antigen. The following differences …

1987-07-01AlgemeenArtikel

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