This literature review will focus on how CRISPR/Cas can be used in curing diabetes. CRISPR is a newly discovered genetical engineering tool that was first found in bacteria and it has an important immune function, protecting them from viral infections by cutting the viral DNA, thereby disabling it. Researchers …

Export shipments arriving late at the freight building of KLM Cargo at Schiphol Airport is a trigger to deviations in the standard acceptance process. These Late Shows are currently handled ad-hoc making it difficult to plan and predict these events. In addition, shipments arriving on time is currently …

In our world of VUCA (volatile, uncertain, complex and ambiguous), a capacity for change and adaption is vital. However, changing successfully has been a challenging task for both individuals and organizations. Taking into account the insights of neuroscience, this chapter introduces a framework of change …

Societal actors across scales and geographies increasingly demand visual applications of systems thinking – the process of understanding and changing the reality of a system by considering its whole set of interdependencies – to address complex problems affecting food and agriculture. Yet, despite the …

Urban experimentation has been increasingly applied as an urban development tool for finding new ways to face grand societal challenges, as they unfold in cities⁠. Experiments might trigger systemic change, since they differ conceptually from conventional urban development, as they can be radical in …

In this study we investigate how consumers in The Netherlands can be persuaded to adopt sustainable practices when purchasing, using and disposing of clothes. This study investigates the attitude-behavior gap for the sustainable choices for purchase, use and disposing of clothes. For each consumption …

Er zijn uitspraken van cliënten die een bepaalde signaalwaarde hebben voor een coach en die alert maken op iets dat van belang kan zijn; die een ‘trigger’ vormen. Triggers doen een impliciet appel op een coach om iets te doen, hoe ambigu dat appel mogelijk ook is. Bijvoorbeeld als een cliënt het woord …

AIM: To contribute to the knowledge and understanding of the active ingredients and mechanisms of change in Motivational Interviewing (MI), to enable MI-counsellors to optimise their MI-strategies in daily practice. METHOD: The body of this dissertation are two multiple case studies, one in 14 patients …

CHI PLAY '20,  November 2–4, 2020, Virtual Event, Canada We have built and implemented a set of metaphors for breathing games by involving children and experts. These games are made to facilitate prevention of asthma exacerbation via regular monitoring of children with asthma through spirometry at …

Recent economic crises, environmental problems and social challenges have urged us to drastically change our consumption and production patterns and transform organisations to contribute to socio-technical transitions that positively impact these challenges. Therefore, sustainable development and the …