Owing to the non-toxic, nonimmunogenic effects and high affinity to specific molecules, some single-stranded oligonucleotides, namely aptamers, can be exploited in biochemical applications to deliver bioactive elements and interact with the desired targets. Among many identified aptamers, D#7 was utilized …

The findings from a bloodstain pattern analysis (BPA) may assist in formulating or falsifying scenarios that are considered in the investigative stages of a criminal investigation. When a case proceeds to trial the bloodstain pattern expert may be asked about the relevance of their findings given scenarios …

Species rich grasslands provide ecosystem services such as floral and faunal diversity, livestock forage, carbon sequestration and water regulation. However, the best combinations of sward diversity and management intensity to achieve the above-mentioned ecosystem services are not fully known. To address …

Dit meesterstuk draait om de sociaaleconomische positie van vrouwen in de Republiek, en de vergelijking met dezelfde positie in de late middeleeuwen. In dit meesterstuk wordt er een poging gedaan om een goed beeld te geven van de verschillende theorieën van historici over dit onderwerp. Hun argumenten …

Psychologist and computerscientist Geoffrey Hinton, called the godfather of AI, argued that we should stop with A(G)I. In this column it is argued that Artificial General Intelligence like ChatGPT works very differently than organic intelligence. An organic complexity works like a chain reaction. Unlike …

In their developmental model, Stodden et al. (2008) propose age- dependent relations between motor competence, physical activity, perceived motor competence, physical fitness, and weight status that can lead to a spiral of (dis)engagement. The goal of this study was to explore these relations in a large …

Native (flat) oyster (Ostrea edulis) beds, once a major component of the North Sea, largely disappeared from the region in the late 19th century. Flat oyster restoration is taking place at a number of locations in the North Sea. When flat oyster beds are restored in areas where O. edulis is functionally …

Rationale: In order to optimize training effects for prevention of sarcopenia and frailty in community dwelling older adults a higher daily protein intake is required. To increase total daily protein intake to optimal levels (minimal 1.2 g/kg/d, optimal 1.5 g/kg/d) during a resistance exercise training …

Background Hospital admissions are common in the last phase of life. However, palliative care and advance care planning (ACP) are provided late or not at all during hospital admission. Aim To provide insight into the perceptions of in-hospital healthcare professionals concerning current and ideal practice …

Movement disorders in dementia are not well known yet they have a devastating effect on the quality of life and the abilities of a person with dementia. Paratonia is one of these movement disorders that are already present in 10% of the population with dementia in the early stages and increase up to …