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Optimal Dosing and Timing of High-Dose Corticosteroid Therapy in Hospitalized Patients With COVID-19

Daenen, Katrijn; Huijben, Jilske A; Boyd, Anders; Bos, Lieuwe D J; Stoof, Sara C M; van Willigen, Hugo; Gommers, Diederik A M P J; Moeniralam, Hazra S; den Uil, Corstiaan A; Juffermans, Nicole P; Kant, Merijn; Valkenburg, Abraham J; Pillay, Janesh; van Meenen, David M P; Paulus, Frederique (Lectoraat Critical Care); Schultz, Marcus J; Dalm, Virgil A S H; van Gorp, Eric C M; Schinkel, Janke; Endeman, Henrik

Background: In hospitalized patients with COVID-19, the dosing and timing of corticosteroids vary widely. Low-dose dexamethasone therapy reduces mortality in patients requiring respiratory support, but it remains unclear how to treat patients when this therapy fails. In critically ill patients, high-dose …

2023-01AlgemeenArtikel

Patients with and without COVID-19 in the Intensive Care Unit: Physical Status Outcome Comparisons 3 Months after Discharge

Bas Cijs (Onderzoeker); Karin Valkenet (Onderzoeker); Germijn Heijnen (Onderzoeker); Anne Visser‑Meily (Onderzoeker); Marike van der Schaaf (Onderzoeker)

Objective: Many patients with COVID-19 infections were admitted to an intensive care unit (ICU). Physical impairments are common after ICU stays and are associated with clinical and patient characteristics. To date, it is unknown if physical functioning and health status are comparable between patients …

2023GezondheidArtikel

Patient outcomes before and after implementation of a selective pre-hospital spinal immobilization protocol

Otto van de Breevaart (Onderzoeker); Nancy van de Waarden (Onderzoeker); Lisette Schoonhoven (Onderzoeker); Wietske Blom-Ham (Onderzoeker); Niels Schep (Onderzoeker)

Background: A new selective preventive spinal immobilization (PSI) protocol was introduced in the Netherlands. This may have led to an increase in non-immobilized spinal fractures (NISFs) and consequently adverse patient outcomes. Aim: A pilot study was conducted to describe the adverse patient outcomes …

2023GezondheidArtikel

Malnutrition risk and frailty in head and neck cancer patients

Dewansingh, Priya; Bras, Linda; Ter Beek, Lies; Krijnen, Wim P (Healthy Ageing, Allied Health Care And Nursing); Roodenburg, Jan L N; van der Schans, Cees P; Halmos, Gyorgy B; Jager-Wittenaar, Harriët (Healthy Ageing, Allied Health Care And Nursing)

PURPOSE: Both malnutrition and frailty are associated with adverse treatment outcomes. Malnutrition (risk) and frailty are each commonly present in patients with head and neck cancer (HNC). However, their coexistence and association is unknown. Main goal of this study is to determine the coexistence …

2022-12-09AlgemeenArtikel

Early high protein provision and mortality in ICU patients including those receiving continuous renal replacement therapy

van Ruijven, Isabel M.; Stapel, Sandra N.; Girbes, Armand R. J.; Weijs, Peter J. M. (Lectoraat Voeding En Beweging)

BACKGROUND: Findings on the association between early high protein provision and mortality in ICU patients are inconsistent. The relation between early high protein provision and mortality in patients receiving CRRT remains unclear. The aim was to study the association between early high protein provision …

2022-09AlgemeenArtikel

Association between Masseter Muscle Area and Thickness and Outcome after Carotid Endarterectomy

Hogenbirk, Rianne N. M.; Banning, Louise B. D.; Visser, Anita; Jager-Wittenaar, Harriët (Malnutrition And Healthy Ageing); Pol, Robert A.; Zeebregts, Clark J.; Klaase, Joost M.

Low muscle mass is associated with adverse outcomes after surgery. This study examined whether facial muscles, such as the masseter muscle, could be used as a proxy for generalized low muscle mass and could be associated with deviant outcomes after carotid endarterectomy (CEA). As a part of the Vascular …

2022-05-30Gezondheid; …Artikel

Calculation of protein requirements

Dekker, Ingeborg M.; van Rijssen, Natascha M.; Verreijen, Amely (Faculteit Bewegen, Sport En Voeding); Weijs, Peter JM (Lectoraat Voeding En Beweging); de Boer, W. B.(Elsbeth); Terpstra, Dominique; Kruizenga, Hinke M.

Background & aims: In dietary practice, it is common to estimate protein requirements on actual bodyweight, but corrected bodyweight (in cases with BMI <20 kg/m2 and BMI ≥30 kg/m2) and fat free mass (FFM) are also used. Large differences on individual level are noticed in protein requirements using these …

2022-04AlgemeenArtikel

Nutritional problems of patients with COVID-19 receiving dietetic treatment in primary care.

A.I. Slotegraaf; Marian de van der Schueren; N.J. Wierdsma; P.J.M. Weijs; H.M. Kruizenga

BACKGROUND: The nutritional problems of patients who are hospitalised for COVID-19 are becoming increasingly clear. However, a large group of patients have never been hospitalised and also appear to experience persistent nutritional problems. The present study describes the nutritional status, risk of …

2022AlgemeenArtikel

Comparison of the prevalence of 21 GLIM phenotypic and etiologic criteria combinations and association with 30-day outcomes in people with cancer: A retrospective observational study.

N Kiss; B. Steer; J Loeliger; R. Alizadehsani; L. Edbrooke; I Deftereos; E. Laing; A. Khosravi; Marian de van der Schueren

BACKGROUND & AIMS: The Global Leadership Initiative on Malnutrition (GLIM) criteria require validation in various clinical populations. This study determined the prevalence of malnutrition in people with cancer using all possible diagnostic combinations of GLIM etiologic and phenotypic criteria and determined …

2022AlgemeenArtikel

Characterization of Social Risk Factors Among Newborns Seen at an Urban Pediatric Primary Care Predictive of Appointment Nonattendance During the First 6 Months of Life.

H. Kersten; K. Courts; K. McPeak; B. Lefchak; A. Cushwa

Purpose: Appointment attendance is critical in monitoring health and well-being of children. Low income Medicaid-insured families with newborns often experience social risks that may affect attendance. This project sought to characterize social risk factors present at first newborn visits predictive …

2022AlgemeenArtikel

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