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Usability and preliminary effectiveness of an app-based physical activity and education program for people with hip or knee osteoarthritis - a pilot randomized controlled trial

Franziska Weber (Onderzoeker); Corelien Kloek (Onderzoeker); Sandra Stuhrmann (Onderzoeker); Yannick Blum (Onderzoeker); Christian Grüneberg (Onderzoeker); Cindy Veenhof (Lector)

Background: Hip and knee osteoarthritis (OA) are highly prevalent worldwide. The guidelines recommend physical activity and education as the core treatments for osteoarthritis. Digital health has the potential to engage people in physical activity and disease management. Therefore, we conducted a pilot …

2024GezondheidArtikel

Microneedling in Abdominal Scarring after DIEP-flap Breast Reconstruction to Improve Scar Quality

Kristel Everaars (Onderzoeker); Audrey Meulendijks (Onderzoeker); Esther Tjin (Onderzoeker); Anne Eskes (Onderzoeker); Stefan Hummelink (Onderzoeker); Erik de Laat (Onderzoeker); Dietmar Ulrich (Onderzoeker)

Background: Deep inferior epigastric perforator (DIEP) flap breast reconstruction leads to large scars in the breast and abdominal region. Common symptoms related to abdominal scarring include changes in color, stiffness, thickness, and irregularity of the skin. The aim of this study was to examine whether …

2024GezondheidArtikel

Development and internal validation of a multivariable prognostic model to predict chronic pain after a new episode of non-specific idiopathic, non-traumatic neck pain in physiotherapy primary care practice

Martine Verwoerd (Onderzoeker); Harriët Wittink (Lector); François Maissan (Onderzoeker); Marc Teunis (Onderzoeker); Sander M.J. van Kuijk (Onderzoeker); Rob Smeets (Onderzoeker)

Objective To develop and internally validate a prognostic model to predict chronic pain after a new episode of acute or subacute non-specific idiopathic, non-traumatic neck pain in patients presenting to physiotherapy primary care, emphasising modifiable biomedical, psychological and social factors. Design …

2024GezondheidArtikel

Lifestyle and health changes in wheelchair users with a chronic disability after 12 weeks of using the WHEELS mHealth application

Hoevenaars, Dirk; Holla, Jasmijn F M; de Groot, Sonja; Weijs, Peter J M (Lectoraat Voeding En Beweging); Kraaij, Wessel; Janssen, Thomas W J

PURPOSE: The aim of this study was to determine changes in physical activity, nutrition, sleep behaviour and body composition in wheelchair users with a chronic disability after 12 weeks of using the WHEELS mHealth application (app). METHODS: A 12-week pre-post intervention study was performed, starting …

2024AlgemeenArtikel

Current practice of hospital-based palliative care teams

van Doorne, Iris (Faculteit Gezondheid); Willems, Dick L.; Baks, Nadine; de Kuijper, Jelle; Buurman, Bianca M.; van Rijn, Marjon (Lectoraat Geïntegreerde Complexe Zorg)

Background Specialist palliative care teams are consulted during hospital admission for advice on complex palliative care. These consultations need to be timely to prevent symptom burden and maintain quality of life. Insight into specialist palliative care teams may help improve the outcomes of palliative …

2024AlgemeenArtikel

The longitudinal relationship between fear of movement and physical activity after cardiac hospitalization

Keessen, Paul (Lectoraat Oefentherapie); Kan, Kees Jan; ter Riet, Gerben; Visser, Bart (Lectoraat Oefentherapie); Jørstad, Harald T.; Latour, Corine H. M. (Lectoraat Geïntegreerde Complexe Zorg); van Duijvenbode, Ingrid C. D. (Lectoraat Oefentherapie); Scholte op Reimer, Wilma J. M.

Background Little is known about the association between fear of movement (kinesiophobia) and objectively measured physical activity (PA), the first 12 weeks after cardiac hospitalization. Purpose To assess the longitudinal association between kinesiophobia and objectively measured PA and to assess the …

2024AlgemeenArtikel

The efficacy of a blended intervention to improve physical activity and protein intake for optimal physical recovery after oncological gastrointestinal and lung cancer surgery, the Optimal Physical Recovery After Hospitalization (OPRAH) trial

de Leeuwerk, Marijke; de Groot, Vincent; Dam, Suzanne ten; Kruizenga, Hinke; Weijs, Peter (Lectoraat Voeding En Beweging); Geleijn, Edwin; van der Leeden, Marike; van der Schaaf, Marike (Lectoraat Revalidatie Bij Complexe Zorg); Dickhoff, Chris; Besselink, Marc G.; Tuynman, Jurriaan B.; van Berge Henegouwen, Mark I.; Erdmann, Joris I.; Huijsmans, Rosalie J.; van der Ploeg, Hidde P.; Eskes, Anne M. (Lectoraat Patiënt- En Familieparticipatie In De Klinische Zorg); Pijnappels, Mirjam A.G.M.; van Leeuwen, Liesbeth Schuijs; Smits, Anke B.; van Dijk, Jasmijn; Grimbergen, Eva

Background: Improving physical activity, especially in combination with optimizing protein intake, after surgery has a potential positive effect on recovery of physical functioning in patients after gastrointestinal and lung cancer surgery. The aim of this randomized controlled trial is to evaluate the …

2023-11-27AlgemeenArtikel

A multidisciplinary lifestyle program for metabolic syndrome-associated osteoarthritis

Walrabenstein, Wendy; Wagenaar, Carlijn A.; van de Put, Marieke; van der Leeden, Marike; Gerritsen, Martijn; Twisk, Jos W.R.; van der Esch, Martin (Lectoraat Interdisciplinaire Zorg Voor Chronische Gewrichtsaandoeningen); van Middendorp, Henriët; Weijs, Peter J.M. (Lectoraat Voeding En Beweging); Roorda, Leo D.; van Schaardenburg, Dirkjan

Objective To determine the effectiveness of the “Plants for Joints” multidisciplinary lifestyle program in patients with metabolic syndrome-associated osteoarthritis (MSOA). Design Patients with hip or knee MSOA were randomized to the intervention or control group. The intervention group followed a 16-week …

2023-11AlgemeenArtikel

L2026M+G2032R variant confers resistance to ROS1 tyrosine kinase inhibitors in SCL34A2-ROS1 overexpressing Ba/F3 cells through a reduced ATP binding pocket volume

Dijkhuizen, Christa (Biomolecules & Health); Korthuis, Patrick; Vilachã, Juliana F.; Smelt, Maaike; van der Wekken, Anthonie; van den Berg, Anke; Drayer, Lyndsay

Background The ROS1 G2032R mutation is the most common on-target resistance mutation in crizotinib treated ROS1-positive lung cancer patients. The aim of our study was to investigate resistance mechanisms in SCL34A2-ROS1G2032R positive Ba/F3 cells against second line treatment with lorlatinib. Methods …

2023-10-21GezondheidConferentiebijdrage

Increasing trends in a low 5-min Apgar score among (near) term singletons: a Dutch nationwide cohort study

C.E. Tacke; W. Onland; P.C.A.M. Bakker; F. Groenendaal; A.N. Rosman; L. Broeders; J.V. Been; A.C.J. Ravelli

Objective To investigate trends in low Apgar scores in (near) term singletons using the Dutch Perinatal Registry. Methods In a cohort of 1,583,188 singletons liveborn ≥35 weeks of gestation in the period 2010–2019, we studied trends in low 5-min Apgar scores (<7 and <4) using Cochrane Armitage trend …

2023-10-18GezondheidArtikel

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