Cyclophosphamide (CPA) is a commonly used alkylating chemotherapeutic drug that targets rapidly dividing cells causing apoptosis by crosslinking DNA. While effective against neoplasms, CPA can also affect healthy immune cells. This study investigated whether a single dose of CPA alters healthy lymphoid …

Clinical outcomes in ROS1-fusion positive (ROS1+) non-small cell lung cancer (NSCLC) by fusion partner and resistance mechanisms are limited. This cohort study included 56 ROS1+ patients (FISH or NGS confirmed); fusion partners were identified in 27 cases, including CD74 (n = 10), EZR (n = 7), and SDC4 …

Purpose The Optimal Physical Recovery After Hospitalization (OPRAH) Intervention is a blended intervention, combining a smartphone app for self-monitoring of physical activity and protein intake with coaching from a physiotherapist and dietician, to enhance the functional recovery after gastro-intestinal …

INTRODUCTION: Standardized training in lung ultrasound is lacking. Given time constraints and challenges in accessing training, there is a need for condensed, focused training programs. This study aims to assess the effect of a targeted, condensed two hour training session on the competency of intensive …

Background The Optimal Physical Recovery After Hospitalization (OPRAH) Intervention is a blended intervention to enhance the functional recovery of patients who had gastro-intestinal or lung cancer surgery. Patients wore an activity tracker to monitor their physical activity and registered their protein …

Deze presentatie neemt je mee in de basisarchitectuur van Large Language Models en laat zien hoe Fenna Feenstra en Wynand Alkema samen met studenten een BERT‑model hebben ontwikkeld om longceltypes te annoteren. Ten slotte bespreken ze de bredere impact van LLM’s op het vakgebied en de kansen die ze …

REducing Delay through edUcation on eXacerbations (REDUX) shows promise in reducing exacerbation recognition and action delays for chronic lung diseases in the Netherlands. However, factors influencing its successful implementation in China remain unclear. To identify the perceived factors influencing …

In this unblinded multi-center stepped-wedge randomized controlled trial the effectiveness of the nurse-led ZENN-intervention was tested in promoting self-management skills in comparison to standard care among heart, lung and kidney transplant recipients. This intervention is based on behaviour change …

Background: Osteoarthritis (OA) is a chronic disease primarily affecting older adults, mainly impacting the hip and knee joints. The increasing prevalence of OA contributes to rising healthcare demands and costs. Current OA treatment guidelines emphasize the importance of self-management education and …