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Feasibility Study to Assess Canagliflozin Distribution and Sodium-Glucose Co-Transporter 2 Occupancy Using [18F]Canagliflozin in Patients with Type 2 Diabetes

van der Hoek, Sjoukje; Willemsen, Antoon T.M.; Visser, Ton; Heeres, Andre (Biobased Chemistry & Refinery); Mulder, Douwe J.; Bokkers, Reinoud P.H.; Slart, Riemer H.J.A.; Elsinga, Philip H.; Heerspink, Hiddo J.L.; Stevens, Jasper

Sodium-glucose co-transporter 2 (SGLT2) inhibitors, including canagliflozin, reduce the risk of cardiovascular and kidney outcomes in patients with and without type 2 diabetes, albeit with a large interindividual variation. The underlying mechanisms for this variation in response might be attributed …

2023-03-10AlgemeenArtikel

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Feasibility Study to Assess Canagliflozin Distribution and Sodium-Glucose Co-Transporter 2 Occupancy Using [18F]Canagliflozin in Patients with Type 2 Diabetes

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