The Netherlands is dependent on artificial structures for water safety. In addition to water safety the artificial structures also provide habitat for different aquatic species. When designing artificial structures like dikes and breakwaters adjustments can be taken to increase species richness or stimulate …

Purpose/Objective: Most dose-escalation trials in glioblastoma patients integrate the escalated dose throughout the standard course by targeting a specific subvolume. We hypothesize that anatomical changes during irradiation may affect the dose coverage of this subvolume for both proton- and photon-based …

Background and purpose: Automatic approaches are widely implemented to automate dose optimization in radiotherapy treatment planning. This study systematically investigates how to configure automatic planning in order to create the best possible plans. Materials and methods: Automatic plans were generated …

a b s t r a c t: Objective: To study the impact of target volume changes in brain metastases during fractionated stereotactic radiosurgery (fSRS) and identify patients that benefit from MRI guidance. Material and methods: For 15 patients (18 lesions) receiving fSRS only (fSRSonly) and 19 patients (20 …

Inleiding In de radiotherapie worden kleine, veel bewegende longtumoren vaak gepland op een Average Intensity Projection (Av-IP) CT. Deze geeft het bewegingsgebied van de tumor met de gemiddelde pixelwaarde weer. Hierdoor ontstaat, bij kleine tumoren, een ‘uitgesmeerde’ tumor met een lage densiteit, …

Met behulp van ConeBeam CT-beelden wordt getoetst of handmatig of automatisch matchen op de tumor gedurende de totale radiotherapiebehandeling bij niet-kleincellige longtumoren accuraat en reproduceerbaar is, met name bij volumevernaderingen. Dit wordt bepaald door middel van target-coverage en interobservervariatie …