Background: Lung fibroblasts are implicated in abnormal tissue repair in chronic obstructive pulmonary disease (COPD). The exact mechanisms are unknown and comprehensive analysis comparing COPD- and control fibroblasts is lacking. Aim: To gain insight in the role of lung fibroblasts in COPD pathology …

Seaweeds from the genus Porphyra play a big economic role in seaweed aquaculture, mainly in Asia. In Europe, resources are put towards seaweed cultivation, but without attention to the Porphyra species which is also native to Europe. Different nomenclature and specifications are used to describe Porphyra, …

Abstract The ever-increasing demand for custom products creates challenges for production companies. In cellular manufacturing systems like the U-shaped assembly cell (USAC), high product variety and fluctuations in demand have become harder to deal with. An increase in flexibility is required to continue …

Skeletal muscle-related symptoms are common in both acute coronavirus disease (Covid)-19 and post-acute sequelae of Covid-19 (PASC). In this narrative review, we discuss cellular and molecular pathways that are affected and consider these in regard to skeletal muscle involvement in other conditions, …

Health care is undergoing a profound technological and digital transformation and has become increasingly complex. It is important for burns professionals and researchers to adapt to these developments which may require new ways of thinking and subsequent new strategies. As Einstein has put it: “We must …

SMPD4 is a neutral sphingomyelinase that plays an important role in sphingolipid metabolism. Sphingolipids are a family of lipid molecules abundantly present in the brain where they play an important role in the brain development and function due to their essential cellular role as structural components …

Protein acylation via metabolic acyl-CoA intermediates provides a link between cellular metabolism and protein functionality. A process in which acetyl-CoA and acetylation are fine-tuned is during myogenic differentiation. However, the roles of other protein acylations remain unknown. Protein propionylation …

Ubiquitin (Ub) is a protein which post-translationally modifies other proteins (its target substrates) and determines their cellular fate. Ub can label substrates for degradation, it can also alter the location of their substrates within a cell or even affect their activity. Chains can be formed via …

Frailty and Physical Therapy講演要旨 （Abstract）The speed of ageing differs from country to country, but ageing is worldwide happening more quickly than in the past. We live in a dangerous world and all kinds of negative influences like stress or poor nutrition causes random molecular damage with an accumulation …

Improvements to the process of carrying out test drives. Conceptualisation and realisation of code to run on microcontroller with the intent of reading telemetry data from a vehicle, containing it in memory and transmitting it to a remote server. Feasibility study on live analysis of the same and more …