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Zocht je misschien: check, chemie?

Effects of Exercise during Chemo- or Radiotherapy on Immune Markers

Anne de Hoop (Onderzoeker); Karin Valkenet (Onderzoeker); Jaap Dronkers (Onderzoeker); Cyrille Krul (Lector); Jelle Ruurda (Onderzoeker); Cindy Veenhof (Lector); Raymond Pieters (Lector)

Introduction: Patients with cancer receiving radio- or chemotherapy undergo many immunological stressors. Chronic regular exercise has been shown to positively influence the immune system in several populations, while exercise overload may have negative effects. Exercise is currently recommended for …

2023GezondheidArtikel

Feasibility of a supervised and home-based tailored exercise intervention in head and neck cancer patients during chemoradiotherapy

Kok, Annemieke; Passchier, Ellen; May, Anne M.; van den Brekel, Michiel W. M.; Jager-Wittenaar, Harriët (Malnutrition And Healthy Ageing); Veenhof, Cindy; de Bree, Remco; Stuiver, Martijn M; Speksnijder, Caroline M.

Objective: Chemoradiotherapy (CRT) for head and neck cancer (HNC) is associated with high toxicity that adversely affects physical functioning, body composition, fatigue, quality of life and treatment outcomes. Exercise interventions during treatment might counteract these negative effects. We therefore …

2022-08-11AlgemeenArtikel

Rol van spiermassa in relatie tot chemo-toxiciteit bij oncologie patiënten

Sealy, Martine

De relatie tussen spiermassa en chemo-toxiciteit en de implicaties hiervan voor de dieetbehandeling en prehabilitatie.

2020-09-28GezondheidConferentiebijdrage

Low muscle mass is associated with early termination of chemotherapy related to toxicity in patients with head and neck cancer

Sealy, Martine J. (Healthy Ageing, Allied Health Care And Nursing); Dechaphunkul, Tanadech; van der Schans, Cees P. (Healthy Ageing, Allied Health Care And Nursing); Krijnen, Wim P (Statistical Techniques For Applied Research); Roodenburg, Jan L. N.; Walker, John; Jager-Wittenaar, Harriët (Malnutrition And Healthy Ageing); Baracos, Vickie E.

BACKGROUND & AIMS: We studied whether low pre-treatment muscle mass, measured with CT at thoracic (T4) or lumbar level (L3) associates with early termination of chemotherapy related to toxicity in head and neck cancer (HNC) patients. METHODS: This was a retrospective chart and image review. Adult HNC …

2020-02AlgemeenArtikel

Study protocol of a prospective multicenter study comparing (cost-)effectiveness of a tailored interdisciplinary head and neck rehabilitation program to usual supportive care for patients treated with concomitant chemo- or bioradiotherapy

Beck, Ann-Jean C C; Passchier, Ellen; Retèl, Valesca P; Stuiver, Martijn M (Centre Of Expertise Urban Vitality); van der Molen, Lisette; Klop, Willem M C; Navran, Arash; van Harten, Wim H; van den Brekel, Michiel W M

BACKGROUND: Since 2011, a tailored, interdisciplinary head and neck rehabilitation (IHNR) program, covered by the basic healthcare insurance, is offered to advanced head and neck cancer (HNC) patients in the Netherlands Cancer Institute (NKI). This program is developed to preserve or restore patients' …

2019-07-03AlgemeenArtikel

Understanding behavioral mechanisms for physical activity in head and neck cancer patients: a qualitative study

Sealy, Martine (Healthy Ageing, Allied Health Care And Nursing); Stuiver, M.M.; Midtgard, Julie; van der Schans, Cees (Healthy Ageing, Allied Health Care And Nursing); Roodenburg, Jan L N; Jager-Wittenaar, Harriët (Malnutrition And Healthy Ageing)

Rationale: Head and neck cancer (HNC) patients often have adverse changes in body composition. Loss of muscle mass and strength frequently occur, even when dietary intake is adequate. Nascent evidence suggests that a healthy lifestyle, including adequate physical activity (PA) and diet, may prevent muscle …

2017-09-08AlgemeenConferentiebijdrage

Prediction model to predict critical weight loss in patients with head and neck cancer during (chemo)radiotherapy

Langius, Jacqueline A.E.; Twisk, Jos; Kampman, Martine; Doornaert, Patricia; Kramer, Mark H.H.; Weijs, Peter J.M. (Lectoraat Voeding En Beweging); Leemans, C. René

OBJECTIVES: Patients with head and neck cancer (HNC) frequently encounter weight loss with multiple negative outcomes as a consequence. Adequate treatment is best achieved by early identification of patients at risk for critical weight loss. The objective of this study was to detect predictive factors …

2016-01AlgemeenArtikel

Effectiveness and cost-utility of a guided self-help exercise program for patients treated with total laryngectomy

Femke Jansen; Ingrid Cnossen (Lid Lectoraat); Simone E.J. Eerenstein; Veerle M.H. Coupé; Birgit I. Witte; Cornelia F. van Uden-Kraan; Patricia Doornaert; Weibel W. Braunius; Remco de Bree; José A.U. Hardillo; Jimmie Honings; György B. Halmos; C. René Leemans; Irma M. Verdonck-de Leeuw

Background Total laryngectomy with or without adjuvant (chemo)radiation often induces speech, swallowing and neck and shoulder problems. Speech, swallowing and shoulder exercises may prevent or diminish these problems. The aim of the present paper is to describe the study, which is designed to investigate …

2016GezondheidArtikel

Geometric changes of parotid glands caused by hydration during chemoradiotherapy

Simon R. van Kranen,; Sanne C. C. van Weerdenburg,; Peter Remeijer; Petronella M. Kager; Olga Hamming-Vrieze; Emmy Kuipers (Lid Lectoraat); Wilma D. Heemsbergen,; Suzanne van Beek,

Abstract: Plan adaptation during the course of (chemo)radiotherapy of H&N cancer requires repeat CT scanning to capture anatomy changes such as parotid gland shrinkage. Hydration, applied to prevent nephrotoxicity from cisplatin, could temporarily alter the hydrogen balance and hence the captured anatomy. …

2015-12-01GezondheidArtikel

De rol van de MRI-neuronavigatie ten opzichte van de vroeg post-operatieve-MRI voor doelvolumedefinitie bij radiotherapie van Glioblastoma Multiforme

Inge Compter (Begeleider); Jirri Groeneweg (Student); Jodocus van Hedel (Begeleider)

Inleiding: Glioblastoma multiforme (GBM) is de meest voorkomende en agressieve vorm van hersentumoren. De behandeling van GBM bestaat uit een resectie met een maand later concurrent chemo-radiotherapie. Binnen 72 uur na de resectie moet de vroeg post-operatieve-magnetic resonance images (MRI) gemaakt …

2015GezondheidBachelor

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