IL22 is an important cytokine involved in the intestinal defense mechanisms against microbiome. By using ileum-derived organoids, we show that the expression of anti-microbial peptides (AMPs) and anti-viral peptides (AVPs) can be induced by IL22. In addition, we identified a bacterial and a viral route, …

Fermentation is known as the oldest method to preserve food and beverages in human history. Also science has picked up on the topic, continuously publishing findings analysing the health effects of consuming lacto-ferments. The Netherlands is amongst the western countries constantly fighting with diet …

PIA (Porcine Intestinal Adenomatose) is een veelvoorkomende varkensziekte die veroorzaakt wordt door de bacterie Lawsonia intracellularis. Deze bacterie veroorzaakt voornamelijk darmontstekingen in het ileum. PIA kan vooral bij vleesvarkens voor problemen zorgen, omdat de aandoening effect heeft op de …

From TU Delft repository: "Intestinal transporter proteins and metabolizing enzymes play a crucial role in the oral absorption of a wide variety of drugs. The aim of the current study was to characterize better available intestinal in vitro models by comparing expression levels of these proteins and …