The primary cause of death in breast cancer cases is often metastasis, the spread of cancer cells systemically and the formation of secondary tumors in distant organs of the body. The invasion of breast tumor cells into the surrounding tissue is an initial step in the metastatic cascade. In addition …

On 2 March 2022, in response to framed and anti-Western narratives surrounding the Russian invasion of Ukraine, the Council of the European Union legally banned two Russian state-sponsored media outlets, RT and Sputnik, within EU borders. The decision of the Council divided opinion. While the ban indeed …

Background and purpose: Automatic approaches are widely implemented to automate dose optimization in radiotherapy treatment planning. This study systematically investigates how to configure automatic planning in order to create the best possible plans. Materials and methods: Automatic plans were generated …

The Urban Gaming studio aims to challenge that by not defining the brief priory (no program, no objectives, no site boundaries). Instead it emphasizes that a client or clients should be sought for, that multiple voices or stakeholders are needed and that a strategy is required to incorporate their needs …

For almost fifteen years, the availability and regulatory acceptance of new approach methodologies (NAMs) to assess the absorption, distribution, metabolism and excretion (ADME/biokinetics) in chemical risk evaluations are a bottleneck. To enhance the field, a team …

This booklet shows the urban metabolism of five different cities around the globe. From small, Venice, to extra large, New York. We took the city as the human body; integral, dependent on multiple organs and based on comprehensive flows. Mobility, typology, nature and history go hand in hand in the total …

Presentatie met Tine Stolte over de plek van kerkorgels in de samenleving

Wilms tumour suppressor gene (WT1) is essential for normal development of a kidney, it was also discovered as a major controller of mesenchymal-epithelial balance in general development of organs. In this project we use Wt1 and its role in the mesenchymal-epithelial balance to study the mechanism of …

Inleiding: Stadium III longkanker (NSCLC) patiënten krijgen veelal te maken met bestralingstoxiciteit aan gezond longweefsel en de organs-at-risk. Om deze toxiciteit te verminderen is in deze studie onderzocht of margereductie van de huidige 10 mm ITV-PTV-bestralingsmarge mogelijk is bij lymfeklier-doelvolumes …

Bestraling van longtumoren blijft een voortdurende uitdaging door beweging tijdens ademhaling (1). Een tumor kan, afhankelijk van de locatie, tot wel 20 millimeter bewegen in inferior-superior richting (2). Een afname van deze beweging kan resulteren in een lagere dosis in omliggende organen, ofwel Organs …