HBO Kennisbank

4 Resultaten

Sorteer op:

Zocht je misschien: proteomic?

A proteomics approach to identify COPD-related changes in lung fibroblasts

Bekker, Nicolaas J.; van Pijkeren, Alienke; Wolters, Justina C.; Sánchez Brotons, Alejandro; Guryev, Victor; Woldhuis, Roy R.; Bischoff, Rainer; Alkema, Wynand (Data Science For Life Science & Health); Horvatovich, Peter; van Nijnatten, Johannes L.L.; van den Berge, Maarten; Timens, Wim; Brandsma, Corry-Anke

Background: Lung fibroblasts are implicated in abnormal tissue repair in chronic obstructive pulmonary disease (COPD). The exact mechanisms are unknown and comprehensive analysis comparing COPD- and control fibroblasts is lacking. Aim: To gain insight in the role of lung fibroblasts in COPD pathology …

2023-04-01AlgemeenArtikel

Sputum Proteome Signatures of Mechanically Ventilated Intensive Care Unit Patients Distinguish Samples with or without Anti-pneumococcal Activity

Seinen, Jolien; Engelke, Rudolf; Abdullah, Mohammed R; Voß, Franziska; Michalik, Stephan; Dhople, Vishnu M; Dieperink, Willem; de Smet, Anne Marie G A; Völker, Uwe; van Dijl, Jan Maarten; Schmidt, Frank; Hammerschmidt, Sven

Respiratory pathogens like Streptococcus pneumoniae can cause severe pneumonia. Nonetheless, mechanically ventilated intensive care patients, who have a high risk of contracting pneumonia, rarely develop pneumococcal pneumonia. Mechanically ventilated patients are at risk of contracting pneumonia. Therefore, …

2021-04-27AlgemeenArtikel

Comparative study using phenotypic, genotypic and proteomics methods for identification of coagulase-negative staphylococci

Anne J. M. Loonen (Lid Lectoraat); Arjan R. Jansz; Jeandery N. B. Bergland; Marion Valkenburg; Petra F. G. Wolffs; Adriaan J. C. van den Brule (Lector)

Five methods were compared to determine the best technique for accurate identification of coagulase-negative staphylococci (CoNS) (n=142 strains). MALDI-TOF MS showed the best results for rapid and accurate CoNS differentiation (correct identity in 99.3%). An alternative to this approach could be Vitek2 …

2012-03-16Natuur & LandbouwArtikel

Urinary protein profiling in hyperactive delirium and non-delirium cardiac surgery ICU patients

R. van Swelm; Hans van der Hoeven; S. Heemskerk; Peter Pickkers; F. Russel; R. Masereeuw; Mark van den Boogaard

Suitable biomarkers associated with the development of delirium are still not known. Urinary proteomics has successfully been applied to identify novel biomarkers associated with various disease states, but its value has not been investigated in delirium patients. In a prospective explorative study hyperactive …

2011AlgemeenArtikel

Vorige Volgende

A proteomics approach to identify COPD-related changes in lung fibroblasts

Sputum Proteome Signatures of Mechanically Ventilated Intensive Care Unit Patients Distinguish Samples with or without Anti-pneumococcal Activity

Comparative study using phenotypic, genotypic and proteomics methods for identification of coagulase-negative staphylococci

Urinary protein profiling in hyperactive delirium and non-delirium cardiac surgery ICU patients

Over HBO Kennisbank