Om inzicht te krijgen in spierveroudering is genexpressie gemeten in vastus lateralis biopten van jonge en oude mannen en vrouwen. We vonden dat tijdens het ouder worden bij beide geslachten dezelfde categorieën genen in spieren worden aan- en uitgeschakeld (“gereguleerd”); de mate van deze zogenaamde …

Lichamelijke zwakte is een belangrijk onderdeel van kwetsbaarheid en komt veel voor bij oudere volwassenen. Terwijl vrouwen een hogere prevalentie en een eerder begin van kwetsbaarheid kennen zijn sekseverschillen in de ontwikkeling van lichamelijke zwakte nauwelijks bestudeerd. Daarom hebben we in spieren …

Training-induced adaptations in muscle morphology, including their magnitude and individual variation, remain relatively unknown in elite athletes. We reported changes in rowing performance and muscle morphology during the general and competitive preparation phases in elite rowers. Nineteen female rowers …

Traumatic knee injuries often lead to long-lasting consequences such as osteoarthritis, pain, and functional limitations. Correct knee alignment and neuromechanics seem to be essential in the prevention of future complaints, however, little is known about which rehabilitation exercises can promote these …

Traumatic knee injuries often lead to long-lasting consequences such as osteoarthritis,pain, and functional limitations. Correct knee alignment and neuromechanics seem to be essential in the prevention of future complaints. During activities involving the knee the vastus medialis obliquus and lateralis …

In deze studie is de betrouwbaarheid van een nieuwe normalisatie methode voor oppervlakte EMG amplitude onderzocht. Deze nieuwe methode is nodig omdat bestaande methodes niet geschikt zijn voor patiënten met Osteo Artrose (OA). Resultaten van deze studie leveren een innovatieve bijdrage aan de revalidatie …

Optimizing physical performance is a major goal in current physiology. However, basic understanding of combining high sprint and endurance performance is currently lacking. This study identifies critical determinants of combined sprint and endurance performance using multiple regression analyses of physiologic …

This review evaluates the reliability and validity of ultrasound to quantify muscles in older adults. The databases PubMed, Cochrane, and Cumulative Index to Nursing and Allied Health Literature were systematically searched for studies. In 17 studies, the reliability (n = 13) and validity (n = 8) of …

Standing up is harder to perform when getting older. The company SillaPlus want to create a physical device that can be attached to already existing chairs and will help elderly people get up from a chair. The company reached out to students who want to help with the development of a get up aid. The …

BACKGROUND: Near-infrared spectroscopy (NIRS) measurements of oxygenation reflect O2 delivery and utilization in exercising muscle and may improve detection of a critical exercise threshold. PURPOSE: First, to detect an oxygenation breakpoint (Δ[O2HbMb-HHbMb]-BP) and compare this breakpoint to ventilatory …