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Effects of exercise during chemotherapy for breast cancer on long-term cardiovascular toxicity

Naaktgeboren, Willeke R.; Stuiver, Martijn M. (Lectoraat Functioneel Herstel Bij Kanker); Van Harten, Wim H.; Aaronson, Neil K.; Scott, Jessica M.; Sonke, Gabe; Van Der Wall, Elsken; Velthuis, Miranda; Leiner, Tim; Teske, Arco J.; May, Anne M.; Groen, Wim G.

Objective Animal data suggest that exercise during chemotherapy is cardioprotective, but clinical evidence to support this is limited. This study evaluated the effect of exercise during chemotherapy for breast cancer on long-term cardiovascular toxicity. Methods This is a follow-up study of two previously …

2023-10-30AlgemeenArtikel

Monitoring physical impact and recovery of pancreatic cancer treatment using consumer wearable health data

van der Schans, Cees P (Healthy Ageing, Allied Health Care And Nursing); van der Schans, Simon; van der Schans, Jurjen; Mylius, Caspar (Healthy Ageing, Allied Health Care And Nursing); Klaase, Joost

Consumer wearables health data may reflect the impact of pancreatic cancer and its treatment on cardiorespiratory fitness and the subsequent recovery after treatment. The patient is a 65-year-old male treated for borderline resectable pancreatic cancer. Treatment consisted of four courses of FOLFIRINOX …

2023-05-22AlgemeenArtikel

Effects of Exercise during Chemo- or Radiotherapy on Immune Markers

Anne de Hoop (Onderzoeker); Karin Valkenet (Onderzoeker); Jaap Dronkers (Onderzoeker); Cyrille Krul (Lector); Jelle Ruurda (Onderzoeker); Cindy Veenhof (Lector); Raymond Pieters (Lector)

Introduction: Patients with cancer receiving radio- or chemotherapy undergo many immunological stressors. Chronic regular exercise has been shown to positively influence the immune system in several populations, while exercise overload may have negative effects. Exercise is currently recommended for …

2023GezondheidArtikel

Effect of physical exercise on the hippocampus and global grey matter volume in breast cancer patients

Koevoets, E.W.; Geerlings, M.I.; Monninkhof, E.M.; Mandl, R.; Witlox, L.; van der Wall, E.; Stuiver, M.M. (Lectoraat Functioneel Herstel Bij Kanker); Sonke, G.S.; Velthuis, M.J.; Jobsen, J.J.; van der Palen, J.; Bos, M.E.M.M.; Göker, E.; Menke-Pluijmers, M.B.E.; Sommeijer, D.W.; May, A.M.; de Ruiter, M.B.; Schagen, S.B.

Background Physical exercise in cancer patients is a promising intervention to improve cognition and increase brain volume, including hippocampal volume. We investigated whether a 6-month exercise intervention primarily impacts total hippocampal volume and additionally hippocampal subfield volumes, cortical …

2023AlgemeenArtikel

Self-monitoring of physical activity after hospital discharge in patients who have undergone gastrointestinal or lung cancer surgery

de Leeuwerk, Marijke Elizabeth; Botjes, Martine; van Vliet, Vincent; Geleijn, Edwin; de Groot, Vincent; van Wegen, Erwin; van der Schaaf, Marike (Faculteit Gezondheid); Tuynman, Jurriaan; Dickhoff, Chris; van der Leeden, Marike

BACKGROUND: Self-monitoring of physical activity (PA) using an accelerometer is a promising intervention to stimulate PA after hospital discharge. OBJECTIVE: This study aimed to evaluate the feasibility of PA self-monitoring after discharge in patients who have undergone gastrointestinal or lung cancer …

2022-06-24AlgemeenArtikel

Physical Fitness and Chemotherapy Tolerance in Patients with Early-Stage Breast Cancer

Groen, Wim G.; Naaktgeboren, Willeke R.; van Harten, Wim H.; van Vulpen, Jonna K.; Kool, Nathalie (Lectoraat Fysiotherapie - Transitie Van Zorg Bij Complexe Patiënten); Sonke, Gabe S.; van der Wall, Elsken; Velthuis, Miranda J.; Aaronson, Neil K.; May, Anne M.; Stuiver, Martijn M. (Lectoraat Functioneel Herstel Bij Kanker)

INTRODUCTION: An optimal relative dose intensity (RDI) of adjuvant chemotherapy is associated with better survival in patients with breast cancer. Little is known about the role of physical fitness in attaining an adequate RDI in patients with early stage breast cancer. We investigated the association …

2022-04AlgemeenArtikel

Are active interventions effective compared to passive non-pharmacological interventions in the treatment of sensory and motor symptoms and improving quality of life in patients diagnosed with chemotherapyinduced peripheral neuropathy?

Susan Schnitter (Student); Caspar Mijlius (Begeleider)

Cancer was diagnosed in 19.292.789 patients worldwide in 2020, depending on the type of cancer treatment may involve chemotherapy. If a neurotoxic agent is used, patients can develop chemotherapy-induced peripheral neuropathy (CIPN) affecting 68% of patients within the first months of treatment. CIPN …

2021-04-17GezondheidBachelor

Cachexia, dietetic consultation, and survival in patients with pancreatic and periampullary cancer: A multicenter cohort study

AEJ Latenstein; WPM Dijksterhuis; TM Mackay; S Beijer; CHJ van Eijck; IHJT de Hingh; IQ Molenaar; MGH van Oijen; HC van Santvoort; Marian de van der Schueren; J de Vos-Geelen; JHM de Vries; JW Wilmink; MG Besselink; HWM van Laarhoven

It is unclear to what extent patients with pancreatic cancer have cachexia and had a dietetic consult for nutritional support. The aim was to assess the prevalence of cachexia, dietitian consultation, and overall survival in these patients. This prospective multicenter cohort study included patients …

2021AlgemeenArtikel

Cachexia and Dietetic Interventions in Patients With Esophagogastric Cancer: A Multicenter Cohort Study

WPM Dijksterhuis; AEJ Latenstein; JJ van Kleef; RHA Verhoeven; JHM de Vries; M Slingerland; E Steenhagen; J Heisterkamp; LM Timmermans; Marian de van der Schueren; MGH van Oijen; S Beijer; HWM van Laarhoven

Background: Cachexia is common in patients with esophagogastric cancer and is associated with increased mortality. Nutritional screening and dietetic interventions can be helpful in preventing evolvement of cachexia. Our aim was to study the real-world prevalence and prognostic value of pretreatment …

2021AlgemeenArtikel

Early Signs of Impaired Gut Function Affect Daily Functioning in Patients With Advanced Cancer Undergoing Chemotherapy

Barbara van der Meij; N.E.P. Deutz; RE Rodriguez; Marscha Engelen

Background Gastrointestinal symptoms are common during chemotherapy, but underlying disturbances in gut function and their impact on daily life are unclear. This study investigates gut function in a heterogenous group of cancer patients with gastrointestinal symptoms during chemotherapy and its relation …

2021AlgemeenArtikel

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