Aims: This systematic review and meta-analysis evaluates the additional effect of exercise to hypocaloric diet on body weight, body composition, glycaemic control and cardio-respiratory fitness in adults with overweight or obesity and type 2 diabetes.  Methods: Embase, Medline, Web of Science and Cochrane …

Machine learning models have proven their use in the medical field, assisting physicians in early diagnosis of serious diseases. Diabetic retinopathy is one of such diseases that could benefit from early detection, but the amount of data available to train accurate models is limited. This challenge could …

This literature review will focus on how CRISPR/Cas can be used in curing diabetes. CRISPR is a newly discovered genetical engineering tool that was first found in bacteria and it has an important immune function, protecting them from viral infections by cutting the viral DNA, thereby disabling it. Researchers …

This poster gives an overview of the project Health and Wellness in a Connected Society. The application of new technological innovations are finding their way into the health and wellness sector where they are increasingly used for various purposes. The research project ‘Health and Wellness in a Connected …

Background: A growing number of mobile health (mHealth) technology–based apps are being developed for personal lifestyle and medical health care support, of which several apps are related to pregnancy. Evidence on usability and effectiveness is limited but crucial for successful implementation. Objective: …

Metformin prevents weight gain in patients with type 2 diabetes (T2D). However, the mechanisms involved are still unknown. In this post hoc analysis of the HOME trial, we aimed to determine whether metformin affects energy intake. Patients with T2D were treated with 850 mg metformin or received placebo …

Doelstelling: In deze studie wordt behandeling met de vasculair-endotheliale groeifactor-remmers aflibercept 2.0 mg en ranibizumab 0.3 mg/0.5 mg met elkaar vergeleken. Hierbij wordt gekeken naar het effect van beide behandelingen op de visus na een jaar, gemeten met de Early Treatment Diabetic Retinopathy …

Doelstelling: Diabetische retinopathie (DRP) is een veel voorkomende complicatie bij diabetes. Deze kan zich uiten door micro-aneurysmata, exsudaten, neovascularisatie en maculaoedeem. Dit kan blindheid tot gevolg hebben. Er zijn een aantal risicofactoren die invloed hebben op de ontwikkeling van DRP, …

Het toepassen van groeifactoren bij de behandeling van de diabetische voet heeft als doel de wondgenezing te versnellen. Door te weinig informatie over het toepassen van PRP bij de behandeling van de diabetische voet, is het nog onduidelijk of deze behandeling effectief en efficiënt genoeg blijkt. Hierdoor …

Both exercise training and a lifestyle-intervention program increase UCP3 protein content inskeletal muscle of subjects with reduced glycaemic control, indicating a restoration towards normal UCP3 levels. These data support the idea that UCP3 has a role in the aetiology of type 2 diabetes mellitus