New approach methodologies predicting human cardiotoxicity are of interest to support or even replace in vivo-based drug safety testing. The present study presents an in vitro–in silico approach to predict the effect of inter-individual and inter-ethnic kinetic variations in the cardiotoxicity of R- …

A new viral illness called coronavirus disease 2019 (COVID-19) is currently spreading throughout the world at an alarming rate (Dong et al., 2020). As family nursing practitioners, educators, and researchers, we work from a guiding assumption that health and “illness is a family affair” (Wright & Bell, …

OBJECTIVE: To examine how a healthy lifestyle is related to life expectancy that is free from major chronic diseases. DESIGN: Prospective cohort study. SETTING AND PARTICIPANTS: The Nurses' Health Study (1980-2014; n=73 196) and the Health Professionals Follow-Up Study (1986-2014; n=38 366). MAIN EXPOSURES: …

KLM has revealed the plan to downsize the full-freight cargo fleet in Schiphol Airport, for that reason the company requires to explore the consequences of moving the cargo transported by the full freighters into the bellies of the passenger flights. In this study, the authors analyze the implications …

This thesis investigates the vulnerability of the crop production towards extreme weather events in the Drentsche Aa Catchment Area in the future years (From 2085 to 2115) and attempts to find the best solution for dealing with the vulnerability. The main method that has been used is literature study …

Nutrient profiling is defined as the science of categorising foods based on their nutrient composition. The Choices Programme is a nutrient profile system with criteria that determine whether foods are eligible to carry a ‘‘healthier option’’ stamp. The Daily Menu Method which has been developed to evaluate …

The goal of the SLIK project is to build and operate the first full-scale wastewater treatment plant to treat the sewage containing rests of medicines and hormones from the Isala hospital in Zwolle. To obtain more insights on the treatment steps, operational aspects and costs through the project can …

The Zhanghe irrigation system (ZIS) is located in the Yangtze River Basin approximately 200 km west of Wuhan in Hubei Province. The reservoir was designed for multiple uses—irrigation, flood control, domestic water supply, industrial use, aquaculture, and hydropower. Over a period of more than 30 years …