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Dysphagia, trismus and speech impairment following radiation-based treatment for advanced stage oropharyngeal carcinoma: a one-year prospective evaluation

Karsten, Rebecca T.; Chargi, Najiba; van der Molen, Lisette; van Son, Rob J. J. H.; de Bree, Remco; Al-Mamgani, Abrahim; de Boer, Jan P.; Hilgers, Frans J. M.; van den Brekel, Michiel W. M.; Smeele, Ludi E.; Stuiver, Martijn M. (Lectoraat Functioneel Herstel Bij Kanker)

OBJECTIVE: The objective was to assess swallowing, mouth opening and speech function during the first year after radiation-based treatment (RT(+)) after introduction of a dedicated preventive rehabilitation program for stage III-IV oropharyngeal carcinoma (OPC). METHODS: Swallowing, mouth opening and …

2022AlgemeenArtikel

Low muscle mass is associated with early termination of chemotherapy related to toxicity in patients with head and neck cancer

Sealy, Martine J. (Healthy Ageing, Allied Health Care And Nursing); Dechaphunkul, Tanadech; van der Schans, Cees P. (Healthy Ageing, Allied Health Care And Nursing); Krijnen, Wim P (Statistical Techniques For Applied Research); Roodenburg, Jan L. N.; Walker, John; Jager-Wittenaar, Harriët (Malnutrition And Healthy Ageing); Baracos, Vickie E.

BACKGROUND & AIMS: We studied whether low pre-treatment muscle mass, measured with CT at thoracic (T4) or lumbar level (L3) associates with early termination of chemotherapy related to toxicity in head and neck cancer (HNC) patients. METHODS: This was a retrospective chart and image review. Adult HNC …

2020-02AlgemeenArtikel

Durable clinical remission of a skull metastasis under intralesional Viscum album extract therapy

Paul G. Werthmann (Onderzoeker); Roman Huber (Onderzoeker); Gunver S. Kienle (Onderzoeker)

Background Skull metastases are rare, they can eventually cause pain, and can invade the brain. Viscum album extracts (VAEs) are used as an adjuvant treatment in cancer. Methods and Results A 68‐year‐old patient with rectal cancer presented with lung metastases, and metastases to multiple bone sites, …

2018GezondheidArtikel

Comparison between the numerical output of the Maastro and Moffitt Radiomic software implementations for lung and head and neck tumors

Esther Bloemen-van Gurp (Begeleider); Marlon van den Broek (Student)

Een vergelijkingsstudie tussen Maastro Clinic Maastricht en Moffitt cancer center Tampa. De numerieke output van long en hoofdhals kanker verkregen door radiomics software tools worden vergeleken met elkaar.

2016GezondheidBachelor

Dose to the masseter muscle and risk of trismus after chemoradiation for advanced head & neck cancer

S Verheijen (Onderzoeker); Emmy Lamers (Lid Lectoraat)

Purpose / objective: Head and neck cancer patients treated with chemoradiation are at risk for developing trismus (reduced mouth opening). Trismus is often a persisting side-effect and difficult to manage. It impairs eating, speech and oral hygiene, affecting quality of life. Although several studies …

2015-12-01GezondheidAndersoortig materiaal

Evaluation of DVH-based treatment plan verification in addition to gamma passing rates for head and neck IMRT

Visser, Ruurd; Wauben, David J.L.; de Groot, Martijn; Steenbakkers, Roel J.H.M.; Godart, Jeremy; van 't Veld, Aart A.; Langendijk, Johannes A.; Korevaar, Erik W.; Bijl, Hendrik P

Background and purpose: Treatment plan verification of intensity modulated radiotherapy (IMRT) is generally performed with the gamma index (GI) evaluation method, which is difficult to extrapolate to clinical implications. Incorporating Dose Volume Histogram (DVH) information can compensate for this. …

2014-09-01AlgemeenArtikel

Validity of bioelectrical impedance analysis to assess fat-free mass in head and neck cancer patients

Jager-Wittenaar, Harriët (Malnutrition And Healthy Ageing); Dijkstra, Pieter; Earthman, Carrie; Krijnen, Wim (Statistical Techniques For Applied Research); Langendijk, Johannes; van der Laan, Bernard; Pruim, Jan; Roodenburg, Jan

Bioelectrical impedance analysis (BIA) may be used to assess fat free mass (FFM) with reasonable validity based on mean-level comparisons, but differences between BIA and DXA may vary by about 4 kg in an individual patient. These results require confirmation in a larger sample of HNC (Head and neck cancer) …

2014AlgemeenArtikel

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