The primary cause of death in breast cancer cases is often metastasis, the spread of cancer cells systemically and the formation of secondary tumors in distant organs of the body. The invasion of breast tumor cells into the surrounding tissue is an initial step in the metastatic cascade. In addition …

Background: Postoperative complications and readmissions to hospital are factors known to negatively influence the short- and long-term quality of life of patients with gastrointestinal cancer. Active family involvement in activities, such as fundamental care activities, has the potential to improve …

Background Gastrointestinal symptoms are common during chemotherapy, but underlying disturbances in gut function and their impact on daily life are unclear. This study investigates gut function in a heterogenous group of cancer patients with gastrointestinal symptoms during chemotherapy and its relation …

Malnutrition is highly prevalent in patients with foregut tumors comprising head and neck (HNC) and esophageal (EC) cancers, negatively impacting outcomes. International evidence-based guidelines (EBGs) for nutrition care exist; however, translation of research evidence into practice commonly presents …

Cutaneous melanoma is a type of skin cancer that develops from benign melanocytes to one of the most aggressive types of skin tumors in human. In cutaneous melanoma progression, the metastasis phase is the most challenging phase to treat. To enable earlier treatment options, a better understanding of …

Reflection by medical historian Marissa Mika on the work towards and around 'Ebifananyi VII, Staying Alive - Documenting the Uganda Cancer Institute'.

Accurate assessment of TP53 gene status in sporadic tumors and in the germline of individuals at high risk of cancer due to Li–Fraumeni Syndrome (LFS) has important clinical implications for diagnosis, surveillance, and therapy. Genomic data from more than 20,000 cancer genomes provide a wealth of information …

Een vergelijkingsstudie tussen Maastro Clinic Maastricht en Moffitt cancer center Tampa. De numerieke output van long en hoofdhals kanker verkregen door radiomics software tools worden vergeleken met elkaar.

Een vergelijkingsstudie tussen Maastro Clinic Maastricht en Moffitt Cancer Center Tampa. In deze studie is onderzocht (1) of er een verschil is tussen de implementatie en numerieke output van de Maastro en Moffitt Radiomic algoritmen en (2) het vinden van een specifieke instelling …

Purpose / objective: Head and neck cancer patients treated with chemoradiation are at risk for developing trismus (reduced mouth opening). Trismus is often a persisting side-effect and difficult to manage. It impairs eating, speech and oral hygiene, affecting quality of life. Although several studies …