IL-4 and IL-13 are prototypic Th2 cytokines that generate an “alternatively activated” phenotype in macrophages. We used high-density oligonucleotide microarrays to investigate the transcriptional profile induced in human monocytes by IL-13. After 8-h stimulation with IL-13, 142 genes were regulated …

This book contains a practical description of a successful method to guide people that have been standing in the sideline for long periods of time, to them a fitting form of social participation. This can be done through paid or voluntary work, activities aimed at physical or psychological and sociale …

Het doel van dit onderzoek was de effecten van huifbedtherapie bij meervoudig gehandicapten beter te onderbouwen. Huifbedtherapie is het behandelen van patiënten, met uiteenlopende aandoeningen, door middel van het huifbed. Het huifbed is een stalen frame waartussen een zeil is uitgespannen. Onder het …

An analysis was made of the various possible activators of single-chain urokinase-type plasminogen activator (scu-PA) in the dextran sulphate euglobulin fraction (DEF) of human plasma. scu-PA activators were detected in an assay system in which the substrate scu-PA, in physiological concentration (50 …

Apart from tissue-type plasminogen activator (t-PA) and urokinase-type plasminogen activator (u-PA), a third PA appears to occur in human plasma. Its activity is initiated when appropriate triggers of the contact system are added, and the activation depends on the presence of factor XII and prekallikrein …

The specific fibrinolytic properties of both high molecular weight (55 kd) and low molecular weight (30 kd) pro-urokinase from a monkey kidney cell culture were evaluated in a plasma clot lysis system and compared with those of human urokinase. The system was composed of a radiolabelled plasma clot immersed …