A clubfoot is characterized by a three-dimensional deformity with an equinus, varus, cavus and adduction component. Nowadays the Ponseti method is the preferred treatment for clubfeet, aiming to achieve a normal appearing, functional and painless foot. The reoccurrence of clubfoot components in treated …

Scar formation is an important adverse consequence of burns. How patients appraise their scar quality is often studied shortly after sustaining the injury, but information in the long-term is scarce. Our aim was, therefore, to evaluate long-term patient-reported quality of burn scars. Adults with a burn …

Wilms tumour suppressor gene (WT1) is essential for normal development of a kidney, it was also discovered as a major controller of mesenchymal-epithelial balance in general development of organs. In this project we use Wt1 and its role in the mesenchymal-epithelial balance to study the mechanism of …

ADHD en reïficatie Dit proefschrift begint met een quote van de 11-jarige Sylvia, die denkt: “ADHD is net als kanker (…) maar je gaat er niet dood aan”. ADHD is zeker geen ziekte als kanker, maar een concept uit de Diagnostic and Statistical Manual (DSM), waarvan momenteel de 5e editie uit is. De DSM-5 …

One potential renewable energy resource is green gas production through anaerobic digestion (AD). However, only part of the biogas produced (up to 50-60%) contains the combustible methane; the remainder are incombustible gasses with the biggest being carbon dioxide. These gasses are often not used and …

Introduction: Reference values for cardiopulmonary exercise testing (CPET) parameters provide the comparative basis for answering important questions concerning the normalcy of exercise responses in patients, and significantly impacts the clinical decision-making process. Areas covered: The aim of this …

OBJECTIVE: The objective of this study was to identify the prevalence and development of after burn joint limitation by scar contracture. METHODS: In 2011-2012, consecutive patients were enrolled in this prospective multi center cohort study. Eligible were all patients admitted to the 2 participating …

Echografische spierdikte metingen van de m. rectus femoris kunnen gebruikt worden voor het kwantificeren van spiermassaverlies. Wanneer extensief spiermassaverlies optreedt, kan worden gesproken over sarcopenie. Deze metingen kunnen een goede aanvulling zijn op het diagnosticeren van sarcopenie bij ouderen. …

If the length of a piece of paper is measured with a ruler, this is literally measuring a quality of something. On the other hand, a score on a pre-constructed test - an IQ test for example s actually generating an estimate based on empirical data of the extent to which someone will develop (ab)normally …

Background: Current use of smartphone cameras by parents create opportunities for longitudinal home-video-assessments to monitor infant development. We developed and validated a home-video method for parents, enabling Pediatric Physical Therapists to assess infants’ gross motor development with the Alberta …