Cancer is a worldwidehuman health problem.This is why much effortis put in finding solutions and treatments for this disease. One of the emerging adjuvant cancer treatments, hyperthermia, is applied by heating the tumourtissue, and is shown to increase the effects of radio and/ or chemotherapy. Because …

Achtergrond: Decubitus is een ernstige complicatie bij dwarslaesiepatiënten. Een dwarslaesiepatiënt heeft tot 85% kans decubitus te ontwikkelen in zijn of haar leven. Druk of druk in combinatie met schuifkrachten veroorzaken beschadigingen van de huid en onderliggend weefsel, meestal op sacrum (43%), …

SAMENVATTING Achtergrond: Femoroacetabulair impingement, kortweg FAI, ontstaat wanneer er een frequent abnormaal contact is tussen het proximale deel van het femur (de kop van het heupgewricht) en het acetabulum (de kom). Dit kan komen door extra botgroei op het femur (CAM-type FAI) of op het acetabulum …

Achtergrond: Vooralsnog is er geen behandeling bekend welke genezing van artrose kan geven. Vanuit de literatuur zijn er aanwijzingen dat het zinvol is de biomechanische toestand van het artrotische gewricht te herstellen. Met gewrichtsdistractie bij knie- en enkelartrose wordt gepoogd, door middel van …

Glucocorticoids (GCs) such as prednisolone are potent immunosuppressive drugs but suffer from severe adverse effects, including the induction of insulin resistance. Therefore, development of so-called Selective Glucocorticoid Receptor Modulators (SGRM) is highly desirable. Here we describe a non-steroidal …

Previous research has shown clinical effectiveness of dermal substitution; however, in burn wounds, only limited effect has been shown. A problem in burn wounds is the reduced take of the autograft, when the substitute and graft are applied in one procedure. Recently, application of topical negative …

Study Type – Aetiology (individual cohort) Level of Evidence 2b What's known on the subject? and What does the study add? Recent studies have already shown associations between generalized joint hypermobility (GJH) and voiding and defecation dysfunction and/or slow transit constipation. Changes in extracellular …

Single Fiber Reflectance spectroscopy (SFR) can be used to determine tissue optical properties such as scattering and absorption. The SFR technique employs a semi-empirical modal, which contains a parameter that is dependent on the fiber numerical aperture, NA . However, the NA is a wavelength dependent …

BACKGROUND: Burn survivors are frequently faced with disfiguring scars. Various techniques exist to improve scar appearance, such as laser treatment and dermabrasion. Next to that, surgical reconstruction, such as scar excision is an option. This randomized controlled trial investigates whether a larger …

Background Hyperbaric oxygen therapy (HBOT) is used to treat various wound types. However, the possible beneficial and harmful effects of HBOT for acute wounds are unclear. Methods We undertook a systematic review to evaluate the effectiveness of HBOT compared to other interventions on wound healing …