5% to 10% of all cancers are linked to gene mutations inherited from parents. The most common gene related to hereditary cancer is the p53 gene. It is a crucial tumor suppressor. However, the mutated gene is commonly inherited from one generation to another one. The functions of p53 resume to the activation …

Objective To evaluate the effectiveness of psychosomatic therapy versus care as usual in primary care for patients with persistent somatic symptoms (PSS). Methods We conducted a pragmatic, two-armed, randomised controlled trial among primary care patients with PSS in the Netherlands that included 39 …

Community energy can be conceptualized as a social movement, which aims to develop a sustainable, democratic, and localist energy system. Increasingly, community energy initiatives aim to develop citizen-led heating projects. District heating projects are characterized by costly investments, a substantial …

This paper examines the effect of firm-specific factors on the leverage decision of the Indonesian listed firms in the food industry, which is one of the largest and most important industries in Indonesia. In this study, four firm-specific determinants of the capital structure were analyzed using a multivariate …

Background: Community learning is one approach to promote research competencies and to involve nurses and nursing students in research. This study examines the impact of community learning according to participants-both those inside and outside the community-in a joint nursing research project at a hospital. …

This chapter provides insights into the complex and adaptive nature of systems and illustrates key characteristics of such systems. These contribute to an understanding of the challenges in health promotion and imply a need for more context-specific research to evaluate the health promotion interventions. …

Walking meetings are a promising way to reduce unhealthy sedentary behavior at the office. Some aspects of walking meetings are however hard to assess using traditional research approaches that do not account well for the embodied experience of walking meetings. We conducted a series of 16 bodystorming …

INTRODUCTION: In patients with cancer, low muscle mass has been associated with a higher risk of fatigue, poorer treatment outcomes, and mortality. To determine body composition with computed tomography (CT), measuring the muscle quantity at the level of lumbar 3 (L3) is suggested. However, in patients …

Equestrianism is currently facing a range of pressing challenges. These challenges, which are largely based on evolving attitudes to ethics and equine wellbeing, have consequences for the sport’s social licence to operate. The factors that may have contributed to the current situation include overarching …

Bilingual education using a Content and Language Integrated Learning (CLIL) approach is widespread in secondary education throughout Europe and also found further afield. In many contexts CLIL seems to select or attract the more able and more academically-inclined pupils, or only be available to pupils …