OBJECTIVES: Patients with head and neck cancer (HNC) frequently encounter weight loss with multiple negative outcomes as a consequence. Adequate treatment is best achieved by early identification of patients at risk for critical weight loss. The objective of this study was to detect predictive factors …

SAMENVATTING Achtergrond en doel Volgens meerdere onderzoekers is er momenteel weer een derde psychedelische golf gaande en in steeds meer buitenlandse publicaties van wetenschappers klinkt het pleidooi om psychedelica serieus te nemen in de medische en therapeutische praktijk. Hier komt in Nederland …

Middels retrospectief, kwantitatief onderzoek is de positievariatie van de prostaat en het verschil in bewegingsvariatie van prostaat en lymfeklierregio’s geanalyseerd. De huidige CTV-PTV marge voor bestraling van prostaat en lymfeklierregio’s is geëvalueerd met een match op de prostaat als positieverificatie. …

Early detection of reading problems is important to prevent an enduring lag in reading skills. We studied the relationship between speed of word recognition (after six months of grade 1 education) and four kindergarten pre-literacy skills: letter knowledge, phonological awareness and naming speed for …

Background In a large randomized trial, Utrecht PROactive Frailty Intervention Trial (U‐PROFIT), we evaluated the effectiveness of an integrated program on the preservation of daily functioning in older people in primary care that consisted of a frailty identification tool and a multicomponent nurse‐led …

Background: COPD self-management is a complex behavior influenced by many factors. Despite scientific evidence that better disease outcomes can be achieved by enhancing self-management, many COPD patients do not respond to self-management interventions. To move toward more effective self-management interventions, …

Bij de radiotherapie van nasofarynxcarcinomen (NPC) en andere hoofd-hals tumoren wordt een optimale dosisafgifte in het doelgebied beoogd, met een minimale dosis in de Organs At Risk (OAR’s). Dit wordt mogelijk bereikt door de setupfout op het bestralingstoestel te reduceren. Tegenwoordig corrigeren …

OBJECTIVES: To determine the effectiveness of a proactive primary care program on the daily functioning of older people in primary care. DESIGN: Single-blind, three-arm, cluster-randomized controlled trial with 1-year follow-up. SETTING: Primary care setting, 39 general practices in the Netherlands. PARTICIPANTS: …

Full text beschikbaar met HU-account. The aim of this study was to investigate, using a mixed-methods design, the added value of a trained Hospital Elder Life Program (HELP) volunteer to the quality of hospital care in the Netherlands. The trained volunteers daily stimulate older patients, at risk of …

BACKGROUND: To evaluate the effects of nurse-led multifactorial care to prevent disability in community-living older people. METHODS: In a cluster randomized trail, 11 practices (n = 1,209 participants) were randomized to the intervention group, and 13 practices (n = 1,074 participants) were randomized …